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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSA
All Species:
21.82
Human Site:
S76
Identified Species:
43.64
UniProt:
P10619
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10619
NP_000299.2
480
54466
S76
S
Q
K
D
P
E
N
S
P
V
V
L
W
L
N
Chimpanzee
Pan troglodytes
XP_001159669
495
55859
S91
S
Q
K
D
P
E
N
S
P
V
V
L
W
L
N
Rhesus Macaque
Macaca mulatta
XP_001106032
494
55727
S90
S
Q
K
D
P
E
N
S
P
V
V
L
W
L
N
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P16675
474
53826
S71
S
Q
N
D
P
K
N
S
P
V
V
L
W
L
N
Rat
Rattus norvegicus
NP_001011959
456
51197
Q65
H
Y
W
F
V
E
S
Q
N
D
P
K
N
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026662
471
53136
S65
A
Q
N
N
P
Q
G
S
P
L
V
L
W
L
N
Frog
Xenopus laevis
NP_001088109
470
52915
N66
S
Q
K
D
P
S
T
N
P
L
V
L
W
L
N
Zebra Danio
Brachydanio rerio
NP_956844
471
53005
S65
S
Q
K
D
P
V
S
S
P
V
V
L
W
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52717
469
53628
D60
S
Q
N
E
P
S
N
D
P
L
I
F
W
F
N
Sea Urchin
Strong. purpuratus
XP_798670
470
52291
D73
S
E
N
D
P
A
N
D
P
V
V
L
W
M
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L7B2
497
55814
C90
W
L
N
G
G
P
G
C
S
S
M
D
G
F
V
Baker's Yeast
Sacchar. cerevisiae
P38109
508
57620
Y100
Q
W
S
G
Y
M
D
Y
K
D
S
K
H
F
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
94.5
N.A.
N.A.
86.8
78.3
N.A.
N.A.
65.8
61.6
63.1
N.A.
N.A.
N.A.
39.3
47.2
Protein Similarity:
100
95.1
94.9
N.A.
N.A.
92
84.7
N.A.
N.A.
77.7
75.8
77
N.A.
N.A.
N.A.
58.9
65.4
P-Site Identity:
100
100
100
N.A.
N.A.
86.6
6.6
N.A.
N.A.
60
73.3
86.6
N.A.
N.A.
N.A.
46.6
66.6
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
13.3
N.A.
N.A.
86.6
86.6
93.3
N.A.
N.A.
N.A.
66.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.4
28.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.7
44.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
59
0
0
9
17
0
17
0
9
0
0
0
% D
% Glu:
0
9
0
9
0
34
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
9
0
25
9
% F
% Gly:
0
0
0
17
9
0
17
0
0
0
0
0
9
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% I
% Lys:
0
0
42
0
0
9
0
0
9
0
0
17
0
0
0
% K
% Leu:
0
9
0
0
0
0
0
0
0
25
0
67
0
59
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
9
0
0
9
0
% M
% Asn:
0
0
42
9
0
0
50
9
9
0
0
0
9
0
75
% N
% Pro:
0
0
0
0
75
9
0
0
75
0
9
0
0
0
9
% P
% Gln:
9
67
0
0
0
9
0
9
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
67
0
9
0
0
17
17
50
9
9
9
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
9
9
0
0
0
50
67
0
0
0
9
% V
% Trp:
9
9
9
0
0
0
0
0
0
0
0
0
75
0
0
% W
% Tyr:
0
9
0
0
9
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _