KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLAT
All Species:
37.88
Human Site:
Y271
Identified Species:
52.08
UniProt:
P10515
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10515
NP_001922.2
647
68997
Y271
F
E
V
Q
E
E
G
Y
L
A
K
I
L
V
P
Chimpanzee
Pan troglodytes
XP_522180
647
68973
Y271
F
E
V
Q
E
E
G
Y
L
A
K
I
L
V
P
Rhesus Macaque
Macaca mulatta
XP_001107013
647
68918
Y271
F
E
V
Q
E
E
G
Y
L
A
K
I
L
V
P
Dog
Lupus familis
XP_546524
647
68802
Y271
F
E
V
Q
E
E
G
Y
L
A
K
I
L
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMF4
642
67923
Y270
F
E
V
Q
E
E
G
Y
L
A
K
I
L
V
P
Rat
Rattus norvegicus
P08461
632
67147
Y261
F
E
V
Q
E
E
G
Y
L
A
K
I
L
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509202
536
56600
T177
T
R
D
V
P
L
G
T
P
L
C
I
I
V
E
Chicken
Gallus gallus
XP_417933
681
72018
Y300
F
E
V
Q
E
E
G
Y
L
A
K
I
L
V
P
Frog
Xenopus laevis
NP_001082239
628
66845
Y248
F
E
V
P
E
E
G
Y
L
A
K
I
L
V
A
Zebra Danio
Brachydanio rerio
NP_997832
652
69250
Y271
F
E
V
Q
E
E
G
Y
L
A
K
I
M
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609118
512
54233
I155
V
G
Q
L
L
C
I
I
V
P
D
Q
G
S
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19749
507
53448
C150
V
P
I
G
K
L
L
C
I
I
V
D
N
E
A
Sea Urchin
Strong. purpuratus
XP_001190217
487
52117
S130
C
I
I
A
E
Q
E
S
G
V
E
A
F
K
D
Poplar Tree
Populus trichocarpa
XP_002303212
512
55370
I155
K
L
G
E
V
I
A
I
T
V
E
D
E
E
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q5M729
539
58449
V182
K
E
I
Q
V
G
E
V
I
A
I
T
V
E
D
Baker's Yeast
Sacchar. cerevisiae
P12695
482
51800
E125
A
F
K
D
F
K
L
E
D
S
G
S
D
S
K
Red Bread Mold
Neurospora crassa
P20285
458
48601
A101
D
S
G
E
K
D
V
A
V
G
N
P
I
A
I
Conservation
Percent
Protein Identity:
100
99.2
98.1
89.4
N.A.
85.6
85.1
N.A.
70.3
72
72.8
71.9
N.A.
42
N.A.
41.7
39.8
Protein Similarity:
100
99.2
98.6
92.8
N.A.
90.2
89.6
N.A.
74.5
78.4
82.6
78.9
N.A.
53.9
N.A.
55
54.1
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
20
100
86.6
80
N.A.
0
N.A.
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
100
86.6
93.3
N.A.
6.6
N.A.
20
26.6
Percent
Protein Identity:
36.3
N.A.
N.A.
38.6
33.5
36.6
Protein Similarity:
50.2
N.A.
N.A.
53
48.2
48.8
P-Site Identity:
0
N.A.
N.A.
20
0
0
P-Site Similarity:
13.3
N.A.
N.A.
40
13.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
6
0
0
6
6
0
59
0
6
0
6
12
% A
% Cys:
6
0
0
0
0
6
0
6
0
0
6
0
0
0
0
% C
% Asp:
6
0
6
6
0
6
0
0
6
0
6
12
6
0
18
% D
% Glu:
0
59
0
12
59
53
12
6
0
0
12
0
6
18
6
% E
% Phe:
53
6
0
0
6
0
0
0
0
0
0
0
6
0
0
% F
% Gly:
0
6
12
6
0
6
59
0
6
6
6
0
6
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
6
18
0
0
6
6
12
12
6
6
59
12
12
6
% I
% Lys:
12
0
6
0
12
6
0
0
0
0
53
0
0
6
6
% K
% Leu:
0
6
0
6
6
12
12
0
53
6
0
0
48
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
6
0
6
0
0
% N
% Pro:
0
6
0
6
6
0
0
0
6
6
0
6
0
0
42
% P
% Gln:
0
0
6
53
0
6
0
0
0
0
0
6
0
0
0
% Q
% Arg:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
6
0
0
0
0
0
6
0
6
0
6
0
12
6
% S
% Thr:
6
0
0
0
0
0
0
6
6
0
0
6
0
0
0
% T
% Val:
12
0
53
6
12
0
6
6
12
12
6
0
6
48
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
53
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _