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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DLAT All Species: 9.09
Human Site: T200 Identified Species: 12.5
UniProt: P10515 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10515 NP_001922.2 647 68997 T200 P A P T P A A T A S P P T P S
Chimpanzee Pan troglodytes XP_522180 647 68973 N200 P A P T P A A N A S P P T P S
Rhesus Macaque Macaca mulatta XP_001107013 647 68918 T200 P A P T P A A T A S P P I P S
Dog Lupus familis XP_546524 647 68802 P200 A A P T P V A P T L P P T P P
Cat Felis silvestris
Mouse Mus musculus Q8BMF4 642 67923 A199 P A A A P A P A A A P A A P S
Rat Rattus norvegicus P08461 632 67147 A190 P A P A A A P A A A P A A P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509202 536 56600 P106 P P G S S Y P P H L Q V Q L P
Chicken Gallus gallus XP_417933 681 72018 P229 P P P P A A A P S P P P P P S
Frog Xenopus laevis NP_001082239 628 66845 P177 P S V A A A T P S P P P Q S A
Zebra Danio Brachydanio rerio NP_997832 652 69250 T200 A A P P P P A T P T S A P A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609118 512 54233 P84 L P E H I R V P L P A L S P T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19749 507 53448 R79 G N L P K H N R V A L P A L S
Sea Urchin Strong. purpuratus XP_001190217 487 52117 S59 K I T L P A L S P T M E V G T
Poplar Tree Populus trichocarpa XP_002303212 512 55370 P84 P H Q E I G M P S L S P T M T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q5M729 539 58449 H111 S G S D L P P H Q E I G M P S
Baker's Yeast Sacchar. cerevisiae P12695 482 51800 W54 T Q G N L A A W T K K E G D Q
Red Bread Mold Neurospora crassa P20285 458 48601 S30 S L T R W Y A S Y P P H T V V
Conservation
Percent
Protein Identity: 100 99.2 98.1 89.4 N.A. 85.6 85.1 N.A. 70.3 72 72.8 71.9 N.A. 42 N.A. 41.7 39.8
Protein Similarity: 100 99.2 98.6 92.8 N.A. 90.2 89.6 N.A. 74.5 78.4 82.6 78.9 N.A. 53.9 N.A. 55 54.1
P-Site Identity: 100 93.3 93.3 60 N.A. 53.3 53.3 N.A. 6.6 53.3 26.6 33.3 N.A. 6.6 N.A. 13.3 13.3
P-Site Similarity: 100 93.3 93.3 60 N.A. 60 60 N.A. 13.3 60 46.6 46.6 N.A. 20 N.A. 20 33.3
Percent
Protein Identity: 36.3 N.A. N.A. 38.6 33.5 36.6
Protein Similarity: 50.2 N.A. N.A. 53 48.2 48.8
P-Site Identity: 20 N.A. N.A. 13.3 13.3 20
P-Site Similarity: 33.3 N.A. N.A. 13.3 13.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 42 6 18 18 53 48 12 30 18 6 18 18 6 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 6 0 0 0 0 0 0 0 0 0 6 0 % D
% Glu: 0 0 6 6 0 0 0 0 0 6 0 12 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 6 6 12 0 0 6 0 0 0 0 0 6 6 6 0 % G
% His: 0 6 0 6 0 6 0 6 6 0 0 6 0 0 0 % H
% Ile: 0 6 0 0 12 0 0 0 0 0 6 0 6 0 0 % I
% Lys: 6 0 0 0 6 0 0 0 0 6 6 0 0 0 0 % K
% Leu: 6 6 6 6 12 0 6 0 6 18 6 6 0 12 0 % L
% Met: 0 0 0 0 0 0 6 0 0 0 6 0 6 6 0 % M
% Asn: 0 6 0 6 0 0 6 6 0 0 0 0 0 0 0 % N
% Pro: 53 18 42 18 42 12 24 36 12 24 53 48 12 53 12 % P
% Gln: 0 6 6 0 0 0 0 0 6 0 6 0 12 0 6 % Q
% Arg: 0 0 0 6 0 6 0 6 0 0 0 0 0 0 0 % R
% Ser: 12 6 6 6 6 0 0 12 18 18 12 0 6 6 48 % S
% Thr: 6 0 12 24 0 0 6 18 12 12 0 0 30 0 18 % T
% Val: 0 0 6 0 0 6 6 0 6 0 0 6 6 6 6 % V
% Trp: 0 0 0 0 6 0 0 6 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 12 0 0 6 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _