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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLAT
All Species:
37.27
Human Site:
S497
Identified Species:
51.25
UniProt:
P10515
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10515
NP_001922.2
647
68997
S497
K
V
P
E
A
N
S
S
W
M
D
T
V
I
R
Chimpanzee
Pan troglodytes
XP_522180
647
68973
S497
K
V
P
E
A
N
S
S
W
M
D
T
V
I
R
Rhesus Macaque
Macaca mulatta
XP_001107013
647
68918
S497
K
V
P
E
A
N
S
S
W
M
D
T
V
I
R
Dog
Lupus familis
XP_546524
647
68802
S497
K
V
P
E
A
N
S
S
W
L
D
T
V
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMF4
642
67923
S492
K
V
P
E
A
N
S
S
W
M
D
T
V
I
R
Rat
Rattus norvegicus
P08461
632
67147
S482
K
V
P
E
A
N
S
S
W
M
D
T
V
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509202
536
56600
N395
L
D
T
V
I
R
Q
N
H
V
V
D
V
S
V
Chicken
Gallus gallus
XP_417933
681
72018
S531
K
V
P
E
A
N
S
S
W
M
D
T
V
I
R
Frog
Xenopus laevis
NP_001082239
628
66845
S478
K
V
P
E
A
N
S
S
W
M
D
T
V
I
R
Zebra Danio
Brachydanio rerio
NP_997832
652
69250
S502
K
V
P
E
A
N
S
S
W
M
D
T
V
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609118
512
54233
V373
V
I
R
K
Y
D
D
V
D
V
S
V
A
V
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19749
507
53448
H368
S
F
I
R
E
N
H
H
V
D
V
S
V
A
V
Sea Urchin
Strong. purpuratus
XP_001190217
487
52117
V348
K
I
R
Q
Y
H
N
V
D
V
N
I
A
V
T
Poplar Tree
Populus trichocarpa
XP_002303212
512
55370
V373
Y
I
R
Q
Y
N
N
V
N
I
N
V
A
V
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q5M729
539
58449
V400
Y
I
R
Q
F
K
N
V
N
I
N
V
A
V
Q
Baker's Yeast
Sacchar. cerevisiae
P12695
482
51800
D343
I
R
K
F
K
N
V
D
V
S
V
A
V
A
T
Red Bread Mold
Neurospora crassa
P20285
458
48601
S319
Q
F
E
T
V
D
V
S
V
A
V
A
T
P
N
Conservation
Percent
Protein Identity:
100
99.2
98.1
89.4
N.A.
85.6
85.1
N.A.
70.3
72
72.8
71.9
N.A.
42
N.A.
41.7
39.8
Protein Similarity:
100
99.2
98.6
92.8
N.A.
90.2
89.6
N.A.
74.5
78.4
82.6
78.9
N.A.
53.9
N.A.
55
54.1
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
6.6
100
100
100
N.A.
0
N.A.
13.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
100
100
N.A.
33.3
N.A.
20
53.3
Percent
Protein Identity:
36.3
N.A.
N.A.
38.6
33.5
36.6
Protein Similarity:
50.2
N.A.
N.A.
53
48.2
48.8
P-Site Identity:
6.6
N.A.
N.A.
0
13.3
6.6
P-Site Similarity:
53.3
N.A.
N.A.
46.6
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
53
0
0
0
0
6
0
12
24
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
6
0
0
0
12
6
6
12
6
53
6
0
0
0
% D
% Glu:
0
0
6
53
6
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
12
0
6
6
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
6
6
6
6
0
0
0
0
0
0
% H
% Ile:
6
24
6
0
6
0
0
0
0
12
0
6
0
53
0
% I
% Lys:
59
0
6
6
6
6
0
0
0
0
0
0
0
0
0
% K
% Leu:
6
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
48
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
71
18
6
12
0
18
0
0
0
6
% N
% Pro:
0
0
53
0
0
0
0
0
0
0
0
0
0
6
0
% P
% Gln:
6
0
0
18
0
0
6
0
0
0
0
0
0
0
12
% Q
% Arg:
0
6
24
6
0
6
0
0
0
0
0
0
0
0
53
% R
% Ser:
6
0
0
0
0
0
53
59
0
6
6
6
0
6
6
% S
% Thr:
0
0
6
6
0
0
0
0
0
0
0
53
6
0
12
% T
% Val:
6
53
0
6
6
0
12
24
18
18
24
18
71
24
12
% V
% Trp:
0
0
0
0
0
0
0
0
53
0
0
0
0
0
0
% W
% Tyr:
12
0
0
0
18
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _