Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GAA All Species: 20.91
Human Site: Y766 Identified Species: 41.82
UniProt: P10253 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10253 NP_000143.2 952 105319 Y766 G K A E V T G Y F P L G T W Y
Chimpanzee Pan troglodytes XP_001160562 952 105395 Y766 G K A E V T G Y F P L G T W Y
Rhesus Macaque Macaca mulatta XP_001109939 952 105411 Y766 G K A E V T G Y F P S G T W Y
Dog Lupus familis XP_850649 951 105652 Y766 G K V E V T G Y F P A G T W Y
Cat Felis silvestris
Mouse Mus musculus P70699 953 106229 Y766 G K T E V T G Y F P K G T W Y
Rat Rattus norvegicus Q6P7A9 953 106188 Y766 G K T D V T G Y F P K G M W Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232641 930 104640 S745 R Q F L W G Q S L L V T P V L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921957 882 99143 I698 L W G S S L L I S P V L E Q G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392880 865 100033 F681 F Y T K D S L F A L G K Y Y T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787183 1049 116156 V862 E A L L V S P V L T K G A T T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7Y7 915 102380 L712 G K T E V E A L F P P G S W Y
Baker's Yeast Sacchar. cerevisiae P38138 954 110248 M764 P G Q S E T E M V F P P G I F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 95.4 83.9 N.A. 80 81.3 N.A. N.A. 50.4 N.A. 53.2 N.A. N.A. 37.7 N.A. 43
Protein Similarity: 100 98.9 97.6 89.5 N.A. 88.4 88.2 N.A. N.A. 66 N.A. 67.7 N.A. N.A. 53.1 N.A. 56.8
P-Site Identity: 100 100 93.3 86.6 N.A. 86.6 73.3 N.A. N.A. 0 N.A. 6.6 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 100 93.3 86.6 N.A. 86.6 80 N.A. N.A. 13.3 N.A. 13.3 N.A. N.A. 26.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 32.7 23 N.A.
Protein Similarity: N.A. N.A. N.A. 50.5 43.7 N.A.
P-Site Identity: N.A. N.A. N.A. 60 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 25 0 0 0 9 0 9 0 9 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 0 50 9 9 9 0 0 0 0 0 9 0 0 % E
% Phe: 9 0 9 0 0 0 0 9 59 9 0 0 0 0 9 % F
% Gly: 59 9 9 0 0 9 50 0 0 0 9 67 9 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 9 0 0 0 0 0 9 0 % I
% Lys: 0 59 0 9 0 0 0 0 0 0 25 9 0 0 0 % K
% Leu: 9 0 9 17 0 9 17 9 17 17 17 9 0 0 9 % L
% Met: 0 0 0 0 0 0 0 9 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 0 0 0 0 0 9 0 0 67 17 9 9 0 0 % P
% Gln: 0 9 9 0 0 0 9 0 0 0 0 0 0 9 0 % Q
% Arg: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 17 9 17 0 9 9 0 9 0 9 0 0 % S
% Thr: 0 0 34 0 0 59 0 0 0 9 0 9 42 9 17 % T
% Val: 0 0 9 0 67 0 0 9 9 0 17 0 0 9 0 % V
% Trp: 0 9 0 0 9 0 0 0 0 0 0 0 0 59 0 % W
% Tyr: 0 9 0 0 0 0 0 50 0 0 0 0 9 9 59 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _