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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GAA
All Species:
26.67
Human Site:
Y543
Identified Species:
53.33
UniProt:
P10253
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10253
NP_000143.2
952
105319
Y543
N
E
L
E
N
P
P
Y
V
P
G
V
V
G
G
Chimpanzee
Pan troglodytes
XP_001160562
952
105395
Y543
N
E
L
E
N
P
P
Y
V
P
G
V
V
G
G
Rhesus Macaque
Macaca mulatta
XP_001109939
952
105411
Y543
N
E
L
E
E
P
P
Y
V
P
G
V
V
G
G
Dog
Lupus familis
XP_850649
951
105652
Y543
N
D
L
E
N
P
P
Y
V
P
G
V
V
G
G
Cat
Felis silvestris
Mouse
Mus musculus
P70699
953
106229
Y543
N
E
L
E
N
P
P
Y
V
P
G
V
V
G
G
Rat
Rattus norvegicus
Q6P7A9
953
106188
Y543
N
E
L
E
N
P
P
Y
V
P
G
V
V
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232641
930
104640
C529
M
D
G
S
E
E
G
C
P
P
G
E
L
D
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921957
882
99143
K486
C
P
D
S
E
L
E
K
P
P
Y
T
P
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392880
865
100033
D469
H
Y
L
G
F
H
Y
D
L
H
N
T
Y
G
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787183
1049
116156
Y650
N
T
Y
D
N
P
P
Y
V
P
G
V
G
G
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S7Y7
915
102380
F500
G
V
V
A
P
V
G
F
K
T
I
A
T
S
A
Baker's Yeast
Sacchar. cerevisiae
P38138
954
110248
T549
S
I
F
D
G
P
E
T
T
A
P
K
D
L
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
95.4
83.9
N.A.
80
81.3
N.A.
N.A.
50.4
N.A.
53.2
N.A.
N.A.
37.7
N.A.
43
Protein Similarity:
100
98.9
97.6
89.5
N.A.
88.4
88.2
N.A.
N.A.
66
N.A.
67.7
N.A.
N.A.
53.1
N.A.
56.8
P-Site Identity:
100
100
93.3
93.3
N.A.
100
100
N.A.
N.A.
13.3
N.A.
13.3
N.A.
N.A.
13.3
N.A.
66.6
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
N.A.
26.6
N.A.
13.3
N.A.
N.A.
26.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
23
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.5
43.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
9
0
9
0
0
9
% A
% Cys:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
17
9
17
0
0
0
9
0
0
0
0
9
9
0
% D
% Glu:
0
42
0
50
25
9
17
0
0
0
0
9
0
0
0
% E
% Phe:
0
0
9
0
9
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
9
0
9
9
9
0
17
0
0
0
67
0
9
75
50
% G
% His:
9
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
9
% I
% Lys:
0
0
0
0
0
0
0
9
9
0
0
9
0
0
0
% K
% Leu:
0
0
59
0
0
9
0
0
9
0
0
0
9
9
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
59
0
0
0
50
0
0
0
0
0
9
0
0
0
9
% N
% Pro:
0
9
0
0
9
67
59
0
17
75
9
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
17
0
0
0
0
0
0
0
0
0
9
9
% S
% Thr:
0
9
0
0
0
0
0
9
9
9
0
17
9
0
9
% T
% Val:
0
9
9
0
0
9
0
0
59
0
0
59
50
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
9
0
0
0
9
59
0
0
9
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _