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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GAA
All Species:
31.21
Human Site:
Y378
Identified Species:
62.42
UniProt:
P10253
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10253
NP_000143.2
952
105319
Y378
F
H
L
C
R
W
G
Y
S
S
T
A
I
T
R
Chimpanzee
Pan troglodytes
XP_001160562
952
105395
Y378
F
H
L
C
R
W
G
Y
S
S
T
A
I
T
R
Rhesus Macaque
Macaca mulatta
XP_001109939
952
105411
Y378
F
H
L
C
R
W
G
Y
S
S
T
A
I
T
R
Dog
Lupus familis
XP_850649
951
105652
Y378
F
H
L
C
R
W
G
Y
S
S
T
A
I
T
R
Cat
Felis silvestris
Mouse
Mus musculus
P70699
953
106229
Y378
F
H
L
C
R
W
G
Y
S
S
T
A
I
V
R
Rat
Rattus norvegicus
Q6P7A9
953
106188
Y378
F
H
L
C
R
W
G
Y
S
S
T
A
I
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232641
930
104640
Y374
F
H
L
C
R
W
G
Y
G
S
S
N
E
T
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921957
882
99143
P343
L
M
R
Q
A
K
I
P
L
D
V
Q
W
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392880
865
100033
N326
K
D
L
P
Q
F
V
N
E
I
H
S
R
G
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787183
1049
116156
Y483
F
H
L
C
R
W
G
Y
N
S
V
S
G
T
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S7Y7
915
102380
I357
L
L
A
F
L
D
K
I
H
K
I
G
M
K
Y
Baker's Yeast
Sacchar. cerevisiae
P38138
954
110248
Y399
Y
H
Q
C
R
W
N
Y
N
D
E
M
D
V
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
95.4
83.9
N.A.
80
81.3
N.A.
N.A.
50.4
N.A.
53.2
N.A.
N.A.
37.7
N.A.
43
Protein Similarity:
100
98.9
97.6
89.5
N.A.
88.4
88.2
N.A.
N.A.
66
N.A.
67.7
N.A.
N.A.
53.1
N.A.
56.8
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
66.6
N.A.
0
N.A.
N.A.
6.6
N.A.
66.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
73.3
N.A.
0
N.A.
N.A.
26.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
23
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.5
43.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
0
0
0
0
0
0
50
0
0
0
% A
% Cys:
0
0
0
75
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
9
0
0
0
17
0
0
9
0
9
% D
% Glu:
0
0
0
0
0
0
0
0
9
0
9
0
9
0
0
% E
% Phe:
67
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
67
0
9
0
0
9
9
9
0
% G
% His:
0
75
0
0
0
0
0
0
9
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
9
0
9
9
0
50
0
0
% I
% Lys:
9
0
0
0
0
9
9
0
0
9
0
0
0
9
0
% K
% Leu:
17
9
75
0
9
0
0
0
9
0
0
0
0
0
9
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
9
9
0
17
% M
% Asn:
0
0
0
0
0
0
9
9
17
0
0
9
0
9
0
% N
% Pro:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
9
9
0
0
0
0
0
0
9
0
0
0
% Q
% Arg:
0
0
9
0
75
0
0
0
0
0
0
0
9
0
50
% R
% Ser:
0
0
0
0
0
0
0
0
50
67
9
17
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
50
0
0
50
0
% T
% Val:
0
0
0
0
0
0
9
0
0
0
17
0
0
25
0
% V
% Trp:
0
0
0
0
0
75
0
0
0
0
0
0
9
0
9
% W
% Tyr:
9
0
0
0
0
0
0
75
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _