Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GAA All Species: 22.73
Human Site: Y360 Identified Species: 45.45
UniProt: P10253 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10253 NP_000143.2 952 105319 Y360 Q Y L D V V G Y P F M P P Y W
Chimpanzee Pan troglodytes XP_001160562 952 105395 Y360 Q Y L D V V G Y P F M P P Y W
Rhesus Macaque Macaca mulatta XP_001109939 952 105411 Y360 Q Y L D V V G Y P F M P P Y W
Dog Lupus familis XP_850649 951 105652 S360 Q Y L E V V G S P F M P P Y W
Cat Felis silvestris
Mouse Mus musculus P70699 953 106229 Y360 Q Y L D V V G Y P F M P P Y W
Rat Rattus norvegicus Q6P7A9 953 106188 Y360 Q Y L D V V G Y P F M P P Y W
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232641 930 104640 F356 Q Y Q E V I G F P A M P P L W
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921957 882 99143 T325 H L C R W G Y T S T N I T R T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392880 865 100033 N308 D L D Y M D K N N D F T Y N S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787183 1049 116156 K465 Q Y Q D V I G K P F M P P M W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7Y7 915 102380 T339 M D G H K D F T L N P V A Y P
Baker's Yeast Sacchar. cerevisiae P38138 954 110248 R381 K F T D L T G R P F L P P I S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 95.4 83.9 N.A. 80 81.3 N.A. N.A. 50.4 N.A. 53.2 N.A. N.A. 37.7 N.A. 43
Protein Similarity: 100 98.9 97.6 89.5 N.A. 88.4 88.2 N.A. N.A. 66 N.A. 67.7 N.A. N.A. 53.1 N.A. 56.8
P-Site Identity: 100 100 100 86.6 N.A. 100 100 N.A. N.A. 60 N.A. 0 N.A. N.A. 0 N.A. 73.3
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. N.A. 80 N.A. 0 N.A. N.A. 6.6 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 32.7 23 N.A.
Protein Similarity: N.A. N.A. N.A. 50.5 43.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 40 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 9 0 0 9 0 0 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 9 9 59 0 17 0 0 0 9 0 0 0 0 0 % D
% Glu: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 9 0 0 0 0 9 9 0 67 9 0 0 0 0 % F
% Gly: 0 0 9 0 0 9 75 0 0 0 0 0 0 0 0 % G
% His: 9 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 17 0 0 0 0 0 9 0 9 0 % I
% Lys: 9 0 0 0 9 0 9 9 0 0 0 0 0 0 0 % K
% Leu: 0 17 50 0 9 0 0 0 9 0 9 0 0 9 0 % L
% Met: 9 0 0 0 9 0 0 0 0 0 67 0 0 9 0 % M
% Asn: 0 0 0 0 0 0 0 9 9 9 9 0 0 9 0 % N
% Pro: 0 0 0 0 0 0 0 0 75 0 9 75 75 0 9 % P
% Gln: 67 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 9 0 0 0 9 0 0 0 0 0 9 0 % R
% Ser: 0 0 0 0 0 0 0 9 9 0 0 0 0 0 17 % S
% Thr: 0 0 9 0 0 9 0 17 0 9 0 9 9 0 9 % T
% Val: 0 0 0 0 67 50 0 0 0 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 67 % W
% Tyr: 0 67 0 9 0 0 9 42 0 0 0 0 9 59 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _