KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GAA
All Species:
23.64
Human Site:
Y148
Identified Species:
47.27
UniProt:
P10253
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10253
NP_000143.2
952
105319
Y148
L
S
S
S
E
M
G
Y
T
A
T
L
T
R
T
Chimpanzee
Pan troglodytes
XP_001160562
952
105395
Y148
L
S
S
S
E
M
G
Y
T
A
T
L
T
R
T
Rhesus Macaque
Macaca mulatta
XP_001109939
952
105411
Y148
L
S
A
S
E
M
G
Y
T
A
T
L
T
R
T
Dog
Lupus familis
XP_850649
951
105652
Y148
L
T
T
T
E
T
G
Y
T
A
A
L
T
R
S
Cat
Felis silvestris
Mouse
Mus musculus
P70699
953
106229
Y148
L
S
S
T
E
S
G
Y
T
A
T
L
T
R
T
Rat
Rattus norvegicus
Q6P7A9
953
106188
Y148
L
S
S
T
E
S
G
Y
T
A
T
L
T
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232641
930
104640
M144
L
N
Q
T
A
L
G
M
T
G
L
L
V
R
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921957
882
99143
E118
L
Q
L
D
V
M
A
E
T
Q
D
R
L
H
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392880
865
100033
Y101
Y
D
A
F
K
K
R
Y
E
P
P
W
P
L
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787183
1049
116156
F252
P
T
P
T
N
Y
G
F
T
A
N
L
T
R
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S7Y7
915
102380
S132
S
G
S
E
L
I
F
S
Y
T
T
D
P
F
T
Baker's Yeast
Sacchar. cerevisiae
P38138
954
110248
F168
F
W
S
K
I
S
S
F
L
S
L
S
N
S
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
95.4
83.9
N.A.
80
81.3
N.A.
N.A.
50.4
N.A.
53.2
N.A.
N.A.
37.7
N.A.
43
Protein Similarity:
100
98.9
97.6
89.5
N.A.
88.4
88.2
N.A.
N.A.
66
N.A.
67.7
N.A.
N.A.
53.1
N.A.
56.8
P-Site Identity:
100
100
93.3
60
N.A.
86.6
86.6
N.A.
N.A.
33.3
N.A.
20
N.A.
N.A.
6.6
N.A.
46.6
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
N.A.
53.3
N.A.
20
N.A.
N.A.
20
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
23
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.5
43.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
9
0
9
0
0
59
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
9
0
0
0
0
0
0
9
9
0
0
0
% D
% Glu:
0
0
0
9
50
0
0
9
9
0
0
0
0
0
0
% E
% Phe:
9
0
0
9
0
0
9
17
0
0
0
0
0
9
0
% F
% Gly:
0
9
0
0
0
0
67
0
0
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
9
9
9
0
0
0
0
0
0
0
0
0
% K
% Leu:
67
0
9
0
9
9
0
0
9
0
17
67
9
9
9
% L
% Met:
0
0
0
0
0
34
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
9
0
0
0
0
0
9
0
9
0
0
% N
% Pro:
9
0
9
0
0
0
0
0
0
9
9
0
17
0
0
% P
% Gln:
0
9
9
0
0
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
9
0
0
0
0
9
0
67
17
% R
% Ser:
9
42
50
25
0
25
9
9
0
9
0
9
0
9
9
% S
% Thr:
0
17
9
42
0
9
0
0
75
9
50
0
59
0
67
% T
% Val:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
9
0
0
0
0
9
0
59
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _