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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TROVE2
All Species:
30
Human Site:
Y46
Identified Species:
60
UniProt:
P10155
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10155
NP_001035828.1
538
60671
Y46
F
G
S
E
G
G
T
Y
Y
I
K
E
Q
K
L
Chimpanzee
Pan troglodytes
XP_001166825
538
60638
Y46
F
G
S
E
G
G
T
Y
Y
I
K
E
Q
K
L
Rhesus Macaque
Macaca mulatta
XP_001105371
205
23292
Dog
Lupus familis
XP_536115
538
60529
Y46
F
G
S
E
G
G
T
Y
Y
I
K
E
Q
K
L
Cat
Felis silvestris
Mouse
Mus musculus
O08848
538
60105
Y46
F
G
S
E
G
G
T
Y
Y
I
K
E
Q
K
L
Rat
Rattus norvegicus
NP_001100653
538
60024
C46
F
G
S
E
G
G
T
C
Y
I
K
E
Q
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516992
539
60168
Y47
F
G
S
E
G
G
T
Y
Y
I
K
E
Q
K
L
Chicken
Gallus gallus
XP_422201
538
60344
Y46
F
G
S
E
G
G
T
Y
C
V
K
E
Q
R
L
Frog
Xenopus laevis
P42700
538
60670
Y46
F
G
S
E
G
G
T
Y
Y
I
E
E
K
K
L
Zebra Danio
Brachydanio rerio
NP_001032474
534
58757
K47
E
S
S
T
Y
S
T
K
E
C
P
L
G
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27274
643
72824
Y93
L
G
S
D
K
G
S
Y
H
Q
S
S
E
K
I
Sea Urchin
Strong. purpuratus
XP_791301
526
58055
C47
K
E
N
P
L
P
E
C
T
Q
T
I
L
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
37.7
97.4
N.A.
89.7
89.5
N.A.
86.4
80.8
78.4
52.9
N.A.
N.A.
N.A.
35.9
36.8
Protein Similarity:
100
100
37.9
99
N.A.
95.3
95.3
N.A.
93.8
90.7
89.5
71.5
N.A.
N.A.
N.A.
52.7
58.3
P-Site Identity:
100
100
0
100
N.A.
100
93.3
N.A.
100
80
86.6
13.3
N.A.
N.A.
N.A.
33.3
0
P-Site Similarity:
100
100
0
100
N.A.
100
93.3
N.A.
100
93.3
100
13.3
N.A.
N.A.
N.A.
66.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
17
9
9
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
9
0
67
0
0
9
0
9
0
9
67
9
9
17
% E
% Phe:
67
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
75
0
0
67
75
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
59
0
9
0
9
9
% I
% Lys:
9
0
0
0
9
0
0
9
0
0
59
0
9
67
0
% K
% Leu:
9
0
0
0
9
0
0
0
0
0
0
9
9
0
67
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
9
0
0
0
0
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
17
0
0
59
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% R
% Ser:
0
9
84
0
0
9
9
0
0
0
9
9
0
0
0
% S
% Thr:
0
0
0
9
0
0
75
0
9
0
9
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
67
59
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _