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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TROVE2 All Species: 34.24
Human Site: T425 Identified Species: 68.48
UniProt: P10155 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10155 NP_001035828.1 538 60671 T425 E M V P C P V T T D M T L Q Q
Chimpanzee Pan troglodytes XP_001166825 538 60638 T425 E M V P C P V T T D M T L Q Q
Rhesus Macaque Macaca mulatta XP_001105371 205 23292 L96 Q E P M L F A L A I C S Q C S
Dog Lupus familis XP_536115 538 60529 T425 E M V P C P V T T D M T L Q Q
Cat Felis silvestris
Mouse Mus musculus O08848 538 60105 T425 D M V P F P V T T D M T L Q Q
Rat Rattus norvegicus NP_001100653 538 60024 T425 D M V P F P V T T D M T L Q Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516992 539 60168 T426 E M V P C P V T A D M T L R Q
Chicken Gallus gallus XP_422201 538 60344 T425 E L V P C P V T A D M T L P Q
Frog Xenopus laevis P42700 538 60670 T425 E M L P C P I T V N M L L H E
Zebra Danio Brachydanio rerio NP_001032474 534 58757 V421 G N L L P C T V S S D M T L M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q27274 643 72824 T529 K L T E L P F T K D W K I G Q
Sea Urchin Strong. purpuratus XP_791301 526 58055 T413 E L K E I P I T A N M K L E D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 37.7 97.4 N.A. 89.7 89.5 N.A. 86.4 80.8 78.4 52.9 N.A. N.A. N.A. 35.9 36.8
Protein Similarity: 100 100 37.9 99 N.A. 95.3 95.3 N.A. 93.8 90.7 89.5 71.5 N.A. N.A. N.A. 52.7 58.3
P-Site Identity: 100 100 0 100 N.A. 86.6 86.6 N.A. 86.6 80 53.3 0 N.A. N.A. N.A. 26.6 33.3
P-Site Similarity: 100 100 13.3 100 N.A. 93.3 93.3 N.A. 93.3 86.6 80 13.3 N.A. N.A. N.A. 46.6 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 0 34 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 50 9 0 0 0 0 9 0 0 9 0 % C
% Asp: 17 0 0 0 0 0 0 0 0 67 9 0 0 0 9 % D
% Glu: 59 9 0 17 0 0 0 0 0 0 0 0 0 9 9 % E
% Phe: 0 0 0 0 17 9 9 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 0 9 0 17 0 0 9 0 0 9 0 0 % I
% Lys: 9 0 9 0 0 0 0 0 9 0 0 17 0 0 0 % K
% Leu: 0 25 17 9 17 0 0 9 0 0 0 9 75 9 0 % L
% Met: 0 59 0 9 0 0 0 0 0 0 75 9 0 0 9 % M
% Asn: 0 9 0 0 0 0 0 0 0 17 0 0 0 0 0 % N
% Pro: 0 0 9 67 9 84 0 0 0 0 0 0 0 9 0 % P
% Gln: 9 0 0 0 0 0 0 0 0 0 0 0 9 42 67 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % R
% Ser: 0 0 0 0 0 0 0 0 9 9 0 9 0 0 9 % S
% Thr: 0 0 9 0 0 0 9 84 42 0 0 59 9 0 0 % T
% Val: 0 0 59 0 0 0 59 9 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _