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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FDX1
All Species:
1.21
Human Site:
S46
Identified Species:
2.22
UniProt:
P10109
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10109
NP_004100.1
184
19393
S46
R
N
R
G
P
G
G
S
A
E
A
S
R
S
L
Chimpanzee
Pan troglodytes
XP_508877
253
26800
D115
L
R
P
P
G
G
V
D
Q
V
V
I
A
I
S
Rhesus Macaque
Macaca mulatta
XP_001105034
184
19299
R46
R
S
R
G
P
G
G
R
A
G
A
S
R
P
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P46656
188
20104
E50
P
S
P
R
L
H
A
E
A
G
P
G
R
P
L
Rat
Rattus norvegicus
P24483
188
20116
E50
P
S
P
H
T
L
A
E
A
G
P
G
R
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508845
318
35033
T180
P
G
R
A
S
P
L
T
C
D
G
E
I
A
P
Chicken
Gallus gallus
P13216
143
15464
L12
A
V
R
T
L
R
P
L
S
L
S
A
R
A
A
Frog
Xenopus laevis
Q5FWQ0
193
21343
Q57
E
E
G
S
S
S
A
Q
I
T
A
G
V
E
S
Zebra Danio
Brachydanio rerio
Q08C57
195
21450
G59
R
R
L
R
T
S
I
G
V
C
Q
S
E
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P37193
172
19715
P39
N
A
L
H
T
T
I
P
R
R
H
G
E
F
E
Honey Bee
Apis mellifera
XP_397185
133
14636
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783792
131
14654
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12184
172
18914
P40
T
T
T
T
R
F
L
P
F
S
T
S
S
F
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.2
96.1
N.A.
N.A.
75
75.5
N.A.
44.3
66.8
34.7
31.2
N.A.
28.2
41.2
N.A.
48.3
Protein Similarity:
100
62.8
97.2
N.A.
N.A.
80.8
81.9
N.A.
50
71.1
52.3
49.2
N.A.
50
54.8
N.A.
58.7
P-Site Identity:
100
6.6
73.3
N.A.
N.A.
20
20
N.A.
6.6
13.3
6.6
13.3
N.A.
0
0
N.A.
0
P-Site Similarity:
100
6.6
80
N.A.
N.A.
26.6
26.6
N.A.
26.6
40
6.6
13.3
N.A.
0
0
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
0
0
24
0
31
0
24
8
8
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
8
0
0
0
8
0
% D
% Glu:
8
8
0
0
0
0
0
16
0
8
0
8
16
8
8
% E
% Phe:
0
0
0
0
0
8
0
0
8
0
0
0
0
16
0
% F
% Gly:
0
8
8
16
8
24
16
8
0
24
8
31
0
0
0
% G
% His:
0
0
0
16
0
8
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
16
0
8
0
0
8
8
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
16
0
16
8
16
8
0
8
0
0
0
0
39
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
24
0
24
8
16
8
8
16
0
0
16
0
0
24
8
% P
% Gln:
0
0
0
0
0
0
0
8
8
0
8
0
0
0
0
% Q
% Arg:
24
16
31
16
8
8
0
8
8
8
0
0
39
0
0
% R
% Ser:
0
24
0
8
16
16
0
8
8
8
8
31
8
8
24
% S
% Thr:
8
8
8
16
24
8
0
8
0
8
8
0
0
0
0
% T
% Val:
0
8
0
0
0
0
8
0
8
8
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _