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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: METT5D2 All Species: 31.21
Human Site: S174 Identified Species: 76.3
UniProt: P0C7V9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P0C7V9 NP_001107000 234 26716 S174 L M D L G C S S M Q L D T P E
Chimpanzee Pan troglodytes XP_508346 407 46088 S174 L M D L G C S S M Q L D T P E
Rhesus Macaque Macaca mulatta XP_001088477 437 49563 S207 L M D L G C S S M Q L D T P E
Dog Lupus familis XP_534100 694 75048 S461 L L D P G C S S M Q L D A P E
Cat Felis silvestris
Mouse Mus musculus Q9DCL4 406 45263 S174 L M D L G C S S M Q L D A P E
Rat Rattus norvegicus NP_001020152 286 31731 S174 L L D L G C S S M Q L D A P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510902 436 48642 S203 L L D L G C S S M Q L D T P E
Chicken Gallus gallus XP_419643 475 52323 S242 L L D A G C S S M Q F D T P E
Frog Xenopus laevis NP_001085383 191 20416 S135 S A G V E P G S I D G V L L D
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795360 187 20857 L131 H K G Q L C P L L G K F S E V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53.3 48.7 26.7 N.A. 39.1 54.2 N.A. 33.2 28.8 39.7 N.A. N.A. N.A. N.A. N.A. 33.7
Protein Similarity: 100 55.7 51 30.6 N.A. 46.7 63.9 N.A. 41.2 38.7 57.6 N.A. N.A. N.A. N.A. N.A. 47.8
P-Site Identity: 100 100 100 80 N.A. 93.3 86.6 N.A. 93.3 80 6.6 N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. 100 86.6 26.6 N.A. N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 0 0 0 0 0 0 0 0 30 0 0 % A
% Cys: 0 0 0 0 0 90 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 80 0 0 0 0 0 0 10 0 80 0 0 10 % D
% Glu: 0 0 0 0 10 0 0 0 0 0 0 0 0 10 80 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % F
% Gly: 0 0 20 0 80 0 10 0 0 10 10 0 0 0 0 % G
% His: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 80 40 0 60 10 0 0 10 10 0 70 0 10 10 0 % L
% Met: 0 40 0 0 0 0 0 0 80 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 10 0 10 10 0 0 0 0 0 0 80 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 80 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 0 0 0 0 80 90 0 0 0 0 10 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 50 0 0 % T
% Val: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _