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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 20.3
Human Site: S27 Identified Species: 37.22
UniProt: P0C6E6 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P0C6E6 NP_056229 105 12063 S27 N L S K P R H S R S L G R P T
Chimpanzee Pan troglodytes XP_529118 105 12047 S27 N V S K P R H S R S L G R P T
Rhesus Macaque Macaca mulatta XP_001100689 105 12293 S27 N V S K P R H S R R R G R L T
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P47964 105 12197 S27 N V S K P R H S R R R S R L T
Rat Rattus norvegicus P39032 105 12249 S27 N V S K P R H S R R R G R L T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506170 105 12279 C27 N I T K P R H C R R R G R L T
Chicken Gallus gallus Q98TF6 105 12277 C27 N V S K P R H C R R R G R L T
Frog Xenopus laevis Q66KU4 105 12307 C27 N V T K P R H C R R R G R L T
Zebra Danio Brachydanio rerio Q6Q415 105 12161 S27 N V S K P K H S R R R G R L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P49630 115 13484 S37 K V K G L R G S R L K N I Q T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P49181 104 11866 R27 T Q L P V K Q R Q N R H K G V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LZ57 108 12171 N27 E Q P P R P N N R K G K T S K
Baker's Yeast Sacchar. cerevisiae O14455 100 11117 A23 K V T Q M T P A P K I S Y K K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 78 N.A. N.A. 74.2 78 N.A. 76.1 76.1 74.2 73.3 N.A. 50.4 N.A. 48.5 N.A.
Protein Similarity: 100 98 80.9 N.A. N.A. 79 81.9 N.A. 81.9 81.9 81.9 80.9 N.A. 66 N.A. 66.6 N.A.
P-Site Identity: 100 93.3 73.3 N.A. N.A. 66.6 73.3 N.A. 60 66.6 60 66.6 N.A. 26.6 N.A. 0 N.A.
P-Site Similarity: 100 100 80 N.A. N.A. 73.3 80 N.A. 73.3 73.3 73.3 80 N.A. 33.3 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 47.2 35.2 N.A.
Protein Similarity: N.A. N.A. N.A. 62 60 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 24 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 0 0 8 0 0 0 8 62 0 8 0 % G
% His: 0 0 0 0 0 0 70 0 0 0 0 8 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 0 8 0 8 0 0 % I
% Lys: 16 0 8 70 0 16 0 0 0 16 8 8 8 8 16 % K
% Leu: 0 8 8 0 8 0 0 0 0 8 16 0 0 54 0 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 70 0 0 0 0 0 8 8 0 8 0 8 0 0 0 % N
% Pro: 0 0 8 16 70 8 8 0 8 0 0 0 0 16 0 % P
% Gln: 0 16 0 8 0 0 8 0 8 0 0 0 0 8 0 % Q
% Arg: 0 0 0 0 8 70 0 8 85 54 62 0 70 0 0 % R
% Ser: 0 0 54 0 0 0 0 54 0 16 0 16 0 8 0 % S
% Thr: 8 0 24 0 0 8 0 0 0 0 0 0 8 0 77 % T
% Val: 0 70 0 0 8 0 0 0 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _