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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO45
All Species:
23.64
Human Site:
T240
Identified Species:
52
UniProt:
P0C2W1
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P0C2W1
NP_001099043.1
286
30633
T240
I
L
D
M
E
D
K
T
L
A
F
E
R
G
Y
Chimpanzee
Pan troglodytes
XP_526475
426
46261
T380
I
L
D
M
E
D
K
T
L
A
F
E
R
G
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851899
283
30439
T237
I
L
D
M
E
D
K
T
L
A
F
E
R
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3B1
286
30586
T240
I
L
D
M
E
D
K
T
L
A
F
E
R
G
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232841
264
29091
A220
D
M
E
D
K
T
L
A
F
E
R
G
Y
E
F
Frog
Xenopus laevis
Q7ZXY1
280
30806
T234
I
L
D
M
E
D
K
T
L
A
F
E
R
G
Y
Zebra Danio
Brachydanio rerio
Q6NZ03
291
31280
T245
I
L
D
M
D
D
K
T
L
A
F
E
R
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6L9
255
28813
S211
D
C
E
D
N
T
L
S
F
E
K
N
Y
E
F
Honey Bee
Apis mellifera
XP_397079
254
28879
L209
L
D
C
D
D
N
T
L
S
F
E
R
N
Y
E
Nematode Worm
Caenorhab. elegans
Q18223
332
36806
V286
I
I
D
C
D
T
H
V
A
Y
F
E
R
N
S
Sea Urchin
Strong. purpuratus
XP_001184356
191
21548
Q147
A
T
R
H
A
S
M
Q
C
Q
G
Y
V
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.5
N.A.
93.3
N.A.
95.4
N.A.
N.A.
N.A.
86.7
81.4
79.3
N.A.
62.5
61.1
44.8
46.1
Protein Similarity:
100
57
N.A.
94.7
N.A.
96.8
N.A.
N.A.
N.A.
87.7
86
88.6
N.A.
73.7
73.7
58.1
56.9
P-Site Identity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
0
100
86.6
N.A.
0
0
33.3
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
26.6
100
100
N.A.
20
20
46.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
10
10
55
0
0
0
10
0
% A
% Cys:
0
10
10
10
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
19
10
64
28
28
55
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
19
0
46
0
0
0
0
19
10
64
0
19
10
% E
% Phe:
0
0
0
0
0
0
0
0
19
10
64
0
0
0
28
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
10
0
55
0
% G
% His:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
64
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
55
0
0
0
10
0
0
0
0
% K
% Leu:
10
55
0
0
0
0
19
10
55
0
0
0
0
0
10
% L
% Met:
0
10
0
55
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
10
0
0
0
0
0
10
10
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
10
10
64
0
0
% R
% Ser:
0
0
0
0
0
10
0
10
10
0
0
0
0
0
10
% S
% Thr:
0
10
0
0
0
28
10
55
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
10
19
10
46
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _