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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C4A
All Species:
4.85
Human Site:
T75
Identified Species:
13.33
UniProt:
P0C0L4
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P0C0L4
NP_009224.2
1744
192771
T75
C
S
P
K
V
D
F
T
L
S
S
E
R
D
F
Chimpanzee
Pan troglodytes
XP_001162503
1744
192821
T75
C
S
P
K
V
D
F
T
L
S
S
E
R
D
F
Rhesus Macaque
Macaca mulatta
XP_001117272
1052
115714
Dog
Lupus familis
XP_538843
1587
174795
P29
C
L
T
A
S
C
F
P
P
G
L
S
C
P
K
Cat
Felis silvestris
Mouse
Mus musculus
P01029
1738
192867
K73
C
S
P
K
K
D
F
K
L
S
S
G
D
D
F
Rat
Rattus norvegicus
P08649
1737
192144
K73
C
S
P
K
K
D
F
K
L
S
S
G
N
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505969
1653
185840
Y70
P
Q
K
R
Q
V
L
Y
N
E
K
I
M
L
S
Chicken
Gallus gallus
P20740
1473
166336
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694622
1697
190715
I70
I
L
S
E
I
R
S
I
I
L
N
E
N
N
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
57.9
72.9
N.A.
76.4
79.6
N.A.
30.5
21.5
N.A.
34
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
58.9
79.5
N.A.
86.7
88.8
N.A.
50.4
40
N.A.
55
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
13.3
N.A.
73.3
73.3
N.A.
0
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
0
13.3
N.A.
73.3
73.3
N.A.
6.6
0
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
56
0
0
0
0
12
0
0
0
0
0
0
12
0
0
% C
% Asp:
0
0
0
0
0
45
0
0
0
0
0
0
12
45
0
% D
% Glu:
0
0
0
12
0
0
0
0
0
12
0
34
0
0
0
% E
% Phe:
0
0
0
0
0
0
56
0
0
0
0
0
0
0
45
% F
% Gly:
0
0
0
0
0
0
0
0
0
12
0
23
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
0
12
0
0
12
12
0
0
12
0
0
0
% I
% Lys:
0
0
12
45
23
0
0
23
0
0
12
0
0
0
12
% K
% Leu:
0
23
0
0
0
0
12
0
45
12
12
0
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
12
0
12
0
23
12
12
% N
% Pro:
12
0
45
0
0
0
0
12
12
0
0
0
0
12
0
% P
% Gln:
0
12
0
0
12
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
12
0
12
0
0
0
0
0
0
23
0
0
% R
% Ser:
0
45
12
0
12
0
12
0
0
45
45
12
0
0
12
% S
% Thr:
0
0
12
0
0
0
0
23
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
23
12
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _