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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLA1
All Species:
37.27
Human Site:
S474
Identified Species:
74.55
UniProt:
P09884
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09884
NP_058633.2
1462
165913
S474
D
L
K
G
E
T
F
S
H
V
F
G
T
N
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001091195
1462
165768
S474
D
L
K
G
E
T
F
S
H
V
F
G
T
N
T
Dog
Lupus familis
XP_537985
1590
179675
S480
D
L
K
G
E
T
F
S
H
V
F
G
T
N
T
Cat
Felis silvestris
Mouse
Mus musculus
P33609
1465
167321
S478
N
L
K
G
E
T
F
S
H
V
F
G
T
N
T
Rat
Rattus norvegicus
O89042
1451
165288
S481
N
L
K
G
E
T
F
S
H
V
F
G
T
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416792
1496
170879
S498
D
L
K
G
E
T
F
S
H
A
F
G
T
N
T
Frog
Xenopus laevis
Q9DE46
1458
165042
S474
D
L
K
G
E
T
F
S
H
V
F
G
T
N
T
Zebra Danio
Brachydanio rerio
XP_001922054
1470
166510
S484
D
L
K
G
T
T
F
S
H
V
F
G
T
N
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26019
1488
169885
Y490
N
L
S
A
D
K
K
Y
N
S
I
A
H
I
F
Honey Bee
Apis mellifera
XP_001121438
1239
142457
R351
Y
S
G
P
S
I
E
R
V
F
G
T
T
V
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FHA3
1492
167126
S493
D
L
K
G
E
S
F
S
A
L
L
G
S
H
T
Baker's Yeast
Sacchar. cerevisiae
P13382
1468
166791
S467
D
T
I
P
S
D
L
S
S
D
T
F
Y
H
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.7
84.4
N.A.
88
89
N.A.
N.A.
73.8
72.5
68.9
N.A.
40
39.4
N.A.
N.A.
Protein Similarity:
100
N.A.
99
87.9
N.A.
92.4
93
N.A.
N.A.
84.8
84.1
82.1
N.A.
58.7
56.1
N.A.
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
N.A.
93.3
100
93.3
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
93.3
100
93.3
N.A.
26.6
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.8
32.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.8
52.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
9
9
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
67
0
0
0
9
9
0
0
0
9
0
0
0
0
0
% D
% Glu:
0
0
0
0
67
0
9
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
75
0
0
9
67
9
0
0
9
% F
% Gly:
0
0
9
75
0
0
0
0
0
0
9
75
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
67
0
0
0
9
17
0
% H
% Ile:
0
0
9
0
0
9
0
0
0
0
9
0
0
9
0
% I
% Lys:
0
0
75
0
0
9
9
0
0
0
0
0
0
0
0
% K
% Leu:
0
84
0
0
0
0
9
0
0
9
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
25
0
0
0
0
0
0
0
9
0
0
0
0
67
9
% N
% Pro:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
0
9
9
0
17
9
0
84
9
9
0
0
9
0
0
% S
% Thr:
0
9
0
0
9
67
0
0
0
0
9
9
75
0
75
% T
% Val:
0
0
0
0
0
0
0
0
9
59
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _