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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLA1
All Species:
34.24
Human Site:
S450
Identified Species:
68.48
UniProt:
P09884
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09884
NP_058633.2
1462
165913
S450
I
P
D
V
P
E
K
S
E
Y
L
E
V
K
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001091195
1462
165768
S450
I
P
D
V
P
E
K
S
E
Y
L
E
V
K
Y
Dog
Lupus familis
XP_537985
1590
179675
S456
I
P
D
V
P
E
K
S
E
Y
L
E
V
R
Y
Cat
Felis silvestris
Mouse
Mus musculus
P33609
1465
167321
S454
I
P
D
V
P
E
K
S
E
Y
L
E
V
R
Y
Rat
Rattus norvegicus
O89042
1451
165288
S457
I
P
D
V
P
E
K
S
E
Y
L
E
V
R
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416792
1496
170879
S474
I
P
D
V
P
A
K
S
E
Y
L
E
V
K
Y
Frog
Xenopus laevis
Q9DE46
1458
165042
S450
I
P
D
V
P
A
S
S
E
Y
L
E
V
R
Y
Zebra Danio
Brachydanio rerio
XP_001922054
1470
166510
S460
I
P
D
I
P
S
Q
S
E
Y
L
E
V
K
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26019
1488
169885
Q466
A
I
G
I
E
V
P
Q
S
C
D
Y
L
E
V
Honey Bee
Apis mellifera
XP_001121438
1239
142457
D327
E
G
T
P
A
I
S
D
Y
L
E
V
R
Y
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FHA3
1492
167126
Q469
P
D
V
P
A
G
E
Q
Y
V
L
K
I
N
Y
Baker's Yeast
Sacchar. cerevisiae
P13382
1468
166791
S443
L
P
D
I
P
S
E
S
D
Y
L
K
V
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.7
84.4
N.A.
88
89
N.A.
N.A.
73.8
72.5
68.9
N.A.
40
39.4
N.A.
N.A.
Protein Similarity:
100
N.A.
99
87.9
N.A.
92.4
93
N.A.
N.A.
84.8
84.1
82.1
N.A.
58.7
56.1
N.A.
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
93.3
80
80
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
93.3
86.6
93.3
N.A.
20
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.8
32.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.8
52.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
17
17
0
0
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
9
75
0
0
0
0
9
9
0
9
0
0
0
0
% D
% Glu:
9
0
0
0
9
42
17
0
67
0
9
67
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
9
0
0
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
67
9
0
25
0
9
0
0
0
0
0
0
9
0
0
% I
% Lys:
0
0
0
0
0
0
50
0
0
0
0
17
0
34
0
% K
% Leu:
9
0
0
0
0
0
0
0
0
9
84
0
9
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
9
75
0
17
75
0
9
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
17
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
9
34
0
% R
% Ser:
0
0
0
0
0
17
17
75
9
0
0
0
0
0
0
% S
% Thr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
9
59
0
9
0
0
0
9
0
9
75
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
17
75
0
9
0
9
75
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _