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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLA1
All Species:
13.03
Human Site:
S315
Identified Species:
26.06
UniProt:
P09884
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09884
NP_058633.2
1462
165913
S315
D
I
D
Q
E
G
D
S
S
F
S
V
Q
E
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001091195
1462
165768
S315
D
I
D
Q
E
G
D
S
S
F
S
V
Q
E
V
Dog
Lupus familis
XP_537985
1590
179675
S321
D
I
D
Q
E
D
D
S
S
F
S
A
Q
E
V
Cat
Felis silvestris
Mouse
Mus musculus
P33609
1465
167321
S321
D
I
D
Q
D
D
E
S
I
P
Q
E
V
Q
V
Rat
Rattus norvegicus
O89042
1451
165288
N322
D
I
D
Q
K
D
E
N
S
F
L
L
Q
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416792
1496
170879
A339
D
K
V
E
E
D
E
A
D
L
V
A
T
D
V
Frog
Xenopus laevis
Q9DE46
1458
165042
A315
C
W
D
Q
I
D
E
A
E
P
M
T
T
E
I
Zebra Danio
Brachydanio rerio
XP_001922054
1470
166510
P327
E
K
M
E
E
G
K
P
I
E
T
P
V
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26019
1488
169885
D279
D
D
D
E
N
Q
F
D
V
E
K
T
Q
Q
T
Honey Bee
Apis mellifera
XP_001121438
1239
142457
N195
E
F
T
T
Q
I
S
N
I
E
V
T
T
T
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FHA3
1492
167126
V281
N
K
I
R
K
T
E
V
K
S
E
L
G
V
K
Baker's Yeast
Sacchar. cerevisiae
P13382
1468
166791
S300
R
V
N
I
D
S
R
S
N
P
S
T
S
P
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.7
84.4
N.A.
88
89
N.A.
N.A.
73.8
72.5
68.9
N.A.
40
39.4
N.A.
N.A.
Protein Similarity:
100
N.A.
99
87.9
N.A.
92.4
93
N.A.
N.A.
84.8
84.1
82.1
N.A.
58.7
56.1
N.A.
N.A.
P-Site Identity:
100
N.A.
100
86.6
N.A.
40
60
N.A.
N.A.
20
20
26.6
N.A.
20
0
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
86.6
N.A.
60
86.6
N.A.
N.A.
46.6
40
46.6
N.A.
33.3
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.8
32.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.8
52.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
17
0
0
0
17
0
0
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
59
9
59
0
17
42
25
9
9
0
0
0
0
9
0
% D
% Glu:
17
0
0
25
42
0
42
0
9
25
9
9
0
50
0
% E
% Phe:
0
9
0
0
0
0
9
0
0
34
0
0
0
0
9
% F
% Gly:
0
0
0
0
0
25
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
42
9
9
9
9
0
0
25
0
0
0
0
0
9
% I
% Lys:
0
25
0
0
17
0
9
0
9
0
9
0
0
0
9
% K
% Leu:
0
0
0
0
0
0
0
0
0
9
9
17
0
0
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
9
0
9
0
9
0
0
17
9
0
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
9
0
25
0
9
0
9
0
% P
% Gln:
0
0
0
50
9
9
0
0
0
0
9
0
42
17
0
% Q
% Arg:
9
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
9
9
42
34
9
34
0
9
0
0
% S
% Thr:
0
0
9
9
0
9
0
0
0
0
9
34
25
9
9
% T
% Val:
0
9
9
0
0
0
0
9
9
0
17
17
17
9
59
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _