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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLA1
All Species:
20.3
Human Site:
S186
Identified Species:
40.61
UniProt:
P09884
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09884
NP_058633.2
1462
165913
S186
M
I
L
K
K
K
R
S
I
G
A
S
P
N
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001091195
1462
165768
S186
T
I
L
K
K
K
R
S
I
G
A
S
P
N
P
Dog
Lupus familis
XP_537985
1590
179675
S192
M
I
P
K
K
K
R
S
I
G
A
S
L
N
P
Cat
Felis silvestris
Mouse
Mus musculus
P33609
1465
167321
S192
L
I
P
K
K
K
R
S
T
G
A
L
L
N
P
Rat
Rattus norvegicus
O89042
1451
165288
S192
L
I
P
K
K
K
R
S
T
G
A
S
P
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416792
1496
170879
S182
L
V
L
K
R
K
R
S
A
G
M
P
L
N
P
Frog
Xenopus laevis
Q9DE46
1458
165042
L175
I
T
L
K
K
K
K
L
A
G
S
P
L
N
P
Zebra Danio
Brachydanio rerio
XP_001922054
1470
166510
K192
P
I
I
T
L
K
K
K
K
T
L
G
S
P
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26019
1488
169885
A162
G
E
I
K
E
E
P
A
A
T
S
E
K
A
E
Honey Bee
Apis mellifera
XP_001121438
1239
142457
D87
E
I
F
D
D
D
L
D
D
E
S
I
Q
E
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FHA3
1492
167126
S155
T
G
E
G
R
L
S
S
M
F
T
S
S
S
F
Baker's Yeast
Sacchar. cerevisiae
P13382
1468
166791
N166
L
P
S
K
L
R
E
N
L
N
S
S
P
T
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.7
84.4
N.A.
88
89
N.A.
N.A.
73.8
72.5
68.9
N.A.
40
39.4
N.A.
N.A.
Protein Similarity:
100
N.A.
99
87.9
N.A.
92.4
93
N.A.
N.A.
84.8
84.1
82.1
N.A.
58.7
56.1
N.A.
N.A.
P-Site Identity:
100
N.A.
93.3
86.6
N.A.
66.6
80
N.A.
N.A.
53.3
46.6
13.3
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
N.A.
93.3
86.6
N.A.
73.3
86.6
N.A.
N.A.
73.3
66.6
26.6
N.A.
40
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.8
32.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.8
52.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
25
0
42
0
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
9
9
0
9
9
0
0
0
0
0
0
% D
% Glu:
9
9
9
0
9
9
9
0
0
9
0
9
0
9
9
% E
% Phe:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
9
% F
% Gly:
9
9
0
9
0
0
0
0
0
59
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
59
17
0
0
0
0
0
25
0
0
9
0
0
0
% I
% Lys:
0
0
0
75
50
67
17
9
9
0
0
0
9
0
0
% K
% Leu:
34
0
34
0
17
9
9
9
9
0
9
9
34
0
0
% L
% Met:
17
0
0
0
0
0
0
0
9
0
9
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
9
0
9
0
0
0
59
0
% N
% Pro:
9
9
25
0
0
0
9
0
0
0
0
17
34
9
59
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
0
0
0
17
9
50
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
9
0
0
0
9
59
0
0
34
50
17
9
9
% S
% Thr:
17
9
0
9
0
0
0
0
17
17
9
0
0
9
0
% T
% Val:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _