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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLA1 All Species: 15.45
Human Site: S1387 Identified Species: 30.91
UniProt: P09884 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09884 NP_058633.2 1462 165913 S1387 Q P E Y S D K S L Y T Q L C F
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001091195 1462 165768 S1387 R P E Y S D K S L Y T Q L C F
Dog Lupus familis XP_537985 1590 179675 S1393 R P E Y S D K S L Y T Q L C F
Cat Felis silvestris
Mouse Mus musculus P33609 1465 167321 S1391 R P E Y S D K S L Y T Q L C F
Rat Rattus norvegicus O89042 1451 165288 L1377 H F S R N G P L C P A C M K A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416792 1496 170879 A1412 R P E Y S D K A L Y T Q L C F
Frog Xenopus laevis Q9DE46 1458 165042 A1384 R S E Y P E K A L Y T Q L C F
Zebra Danio Brachydanio rerio XP_001922054 1470 166510 A1396 K P E Y S E K A L Y N Q L S F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P26019 1488 169885 D1401 L R Q Y T E R D L Y N Q L C Y
Honey Bee Apis mellifera XP_001121438 1239 142457 Q1165 F H L F N V S Q S K Y K N L L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FHA3 1492 167126 T1417 N Y P N C N G T L L R K Y T E
Baker's Yeast Sacchar. cerevisiae P13382 1468 166791 Y1391 Q L Y N Q L L Y F D S L F D C
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.7 84.4 N.A. 88 89 N.A. N.A. 73.8 72.5 68.9 N.A. 40 39.4 N.A. N.A.
Protein Similarity: 100 N.A. 99 87.9 N.A. 92.4 93 N.A. N.A. 84.8 84.1 82.1 N.A. 58.7 56.1 N.A. N.A.
P-Site Identity: 100 N.A. 93.3 93.3 N.A. 93.3 0 N.A. N.A. 86.6 66.6 66.6 N.A. 40 0 N.A. N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 13.3 N.A. N.A. 100 86.6 86.6 N.A. 73.3 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 34.8 32.2 N.A.
Protein Similarity: N.A. N.A. N.A. 54.8 52.2 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 25 0 0 9 0 0 0 9 % A
% Cys: 0 0 0 0 9 0 0 0 9 0 0 9 0 59 9 % C
% Asp: 0 0 0 0 0 42 0 9 0 9 0 0 0 9 0 % D
% Glu: 0 0 59 0 0 25 0 0 0 0 0 0 0 0 9 % E
% Phe: 9 9 0 9 0 0 0 0 9 0 0 0 9 0 59 % F
% Gly: 0 0 0 0 0 9 9 0 0 0 0 0 0 0 0 % G
% His: 9 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 0 0 0 0 0 59 0 0 9 0 17 0 9 0 % K
% Leu: 9 9 9 0 0 9 9 9 75 9 0 9 67 9 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 9 0 0 17 17 9 0 0 0 0 17 0 9 0 0 % N
% Pro: 0 50 9 0 9 0 9 0 0 9 0 0 0 0 0 % P
% Gln: 17 0 9 0 9 0 0 9 0 0 0 67 0 0 0 % Q
% Arg: 42 9 0 9 0 0 9 0 0 0 9 0 0 0 0 % R
% Ser: 0 9 9 0 50 0 9 34 9 0 9 0 0 9 0 % S
% Thr: 0 0 0 0 9 0 0 9 0 0 50 0 0 9 0 % T
% Val: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 9 67 0 0 0 9 0 67 9 0 9 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _