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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VIL1 All Species: 28.48
Human Site: S259 Identified Species: 62.67
UniProt: P09327 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09327 NP_009058.2 827 92695 S259 A L K L Y H V S D S E G N L V
Chimpanzee Pan troglodytes XP_526028 827 92713 S259 A L K L Y H V S D S E G N L V
Rhesus Macaque Macaca mulatta XP_001090524 827 92643 S259 A L K L Y H V S D A E G N L V
Dog Lupus familis XP_545642 827 92708 S259 A L K L Y H V S D A E G K L V
Cat Felis silvestris
Mouse Mus musculus Q62468 827 92783 S259 A L K L Y H V S D S E G K L V
Rat Rattus norvegicus Q68FP1 780 86049 Q240 F E R L K A T Q V S K G I R D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P02640 826 92461 S259 A L K L Y H V S D A S G N L V
Frog Xenopus laevis P14885 417 46006
Zebra Danio Brachydanio rerio NP_956532 834 93918 S261 A I K L Y H I S D A Q G S L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q07171 798 88356 S294 A D Q V P D E S T A D E D S A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O81645 966 106448 K255 I P E T T P P K L Y S I A D G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.6 88.5 N.A. 90 44.8 N.A. N.A. 71.3 25.2 64.7 N.A. 33.9 N.A. N.A. N.A.
Protein Similarity: 100 99.7 98.3 94 N.A. 94 57.6 N.A. N.A. 82.9 35.3 80.4 N.A. 50.5 N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 86.6 N.A. 93.3 20 N.A. N.A. 86.6 0 66.6 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 33.3 N.A. N.A. 93.3 0 100 N.A. 46.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 46.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 73 0 0 0 0 10 0 0 0 46 0 0 10 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 10 0 0 64 0 10 0 10 10 10 % D
% Glu: 0 10 10 0 0 0 10 0 0 0 46 10 0 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 73 0 0 10 % G
% His: 0 0 0 0 0 64 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 10 0 0 0 0 10 0 0 0 0 10 10 0 0 % I
% Lys: 0 0 64 0 10 0 0 10 0 0 10 0 19 0 0 % K
% Leu: 0 55 0 73 0 0 0 0 10 0 0 0 0 64 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 37 0 0 % N
% Pro: 0 10 0 0 10 10 10 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 10 0 0 10 0 0 0 0 % Q
% Arg: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % R
% Ser: 0 0 0 0 0 0 0 73 0 37 19 0 10 10 0 % S
% Thr: 0 0 0 10 10 0 10 0 10 0 0 0 0 0 0 % T
% Val: 0 0 0 10 0 0 55 0 10 0 0 0 0 0 64 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 64 0 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _