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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMP7
All Species:
22.73
Human Site:
S47
Identified Species:
62.5
UniProt:
P09237
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09237
NP_002414.1
267
29677
S47
K
R
F
Y
L
Y
D
S
E
T
K
N
A
N
S
Chimpanzee
Pan troglodytes
XP_508721
267
29665
S47
K
R
F
Y
L
Y
D
S
E
T
K
N
A
N
S
Rhesus Macaque
Macaca mulatta
XP_001097508
267
29741
S47
K
R
F
Y
L
Y
D
S
E
T
K
N
A
N
S
Dog
Lupus familis
XP_546550
263
29459
S47
K
R
F
Y
P
S
D
S
K
T
R
D
A
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q10738
264
29736
S47
R
K
F
Y
P
H
D
S
K
T
K
K
V
N
S
Rat
Rattus norvegicus
P50280
267
29867
S50
R
K
F
Y
L
H
D
S
K
T
K
K
A
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510024
270
30984
T47
N
N
F
Y
A
S
D
T
E
E
H
A
S
N
F
Chicken
Gallus gallus
Q90611
663
74923
K59
N
K
Y
Y
G
C
P
K
D
N
C
N
L
F
V
Frog
Xenopus laevis
O13065
467
52794
G52
G
T
D
G
G
P
V
G
R
K
K
H
I
Q
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
97.3
76.4
N.A.
69.6
70
N.A.
57.4
20.3
27.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.8
85
N.A.
81.2
82.4
N.A.
74.8
27.2
37.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
60
N.A.
53.3
60
N.A.
33.3
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
80
86.6
N.A.
46.6
33.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
0
0
0
0
0
12
56
0
0
% A
% Cys:
0
0
0
0
0
12
0
0
0
0
12
0
0
0
0
% C
% Asp:
0
0
12
0
0
0
78
0
12
0
0
12
0
12
0
% D
% Glu:
0
0
0
0
0
0
0
0
45
12
0
0
0
0
0
% E
% Phe:
0
0
78
0
0
0
0
0
0
0
0
0
0
12
12
% F
% Gly:
12
0
0
12
23
0
0
12
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
23
0
0
0
0
12
12
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% I
% Lys:
45
34
0
0
0
0
0
12
34
12
67
23
0
0
0
% K
% Leu:
0
0
0
0
45
0
0
0
0
0
0
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
23
12
0
0
0
0
0
0
0
12
0
45
0
56
0
% N
% Pro:
0
0
0
0
23
12
12
0
0
0
0
0
0
0
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% Q
% Arg:
23
45
0
0
0
0
0
0
12
0
12
0
0
0
0
% R
% Ser:
0
0
0
0
0
23
0
67
0
0
0
0
12
0
67
% S
% Thr:
0
12
0
0
0
0
0
12
0
67
0
0
0
12
0
% T
% Val:
0
0
0
0
0
0
12
0
0
0
0
0
12
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
89
0
34
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _