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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENO2
All Species:
25.45
Human Site:
Y25
Identified Species:
43.08
UniProt:
P09104
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09104
NP_001966.1
434
47269
Y25
P
T
V
E
V
D
L
Y
T
A
K
G
L
F
R
Chimpanzee
Pan troglodytes
XP_511294
434
46968
H25
P
T
V
E
V
D
L
H
T
A
K
G
R
F
R
Rhesus Macaque
Macaca mulatta
XP_001110839
434
47224
Y25
P
T
V
E
V
D
L
Y
T
A
K
G
L
F
R
Dog
Lupus familis
XP_534902
434
47168
H25
P
T
V
E
V
D
L
H
T
A
K
G
L
F
R
Cat
Felis silvestris
Mouse
Mus musculus
P17183
434
47278
Y25
P
T
V
E
V
D
L
Y
T
A
K
G
L
F
R
Rat
Rattus norvegicus
P07323
434
47122
H25
P
T
V
E
V
D
L
H
T
A
K
G
L
F
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505468
461
50129
Y25
P
T
V
E
V
D
L
Y
T
G
K
G
L
F
R
Chicken
Gallus gallus
O57391
434
47290
Y25
P
T
V
E
V
D
L
Y
T
H
K
G
M
F
R
Frog
Xenopus laevis
P08734
434
47486
Y25
P
T
V
E
V
D
L
Y
T
C
K
G
L
F
R
Zebra Danio
Brachydanio rerio
NP_001003848
434
46822
R25
P
T
V
E
V
D
L
R
T
D
K
G
L
F
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P15007
500
54292
T92
P
T
V
E
V
D
L
T
T
E
L
G
L
F
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27527
434
46598
F25
P
T
V
E
V
D
L
F
T
E
K
G
V
F
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P42895
446
48144
F27
P
T
V
E
V
D
V
F
C
S
D
G
T
F
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P25696
444
47701
H26
P
T
V
E
V
D
I
H
T
S
N
G
I
K
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.4
99.3
98.8
N.A.
98.6
97.9
N.A.
79.6
91.4
82.2
83.6
N.A.
63.2
N.A.
73.5
N.A.
Protein Similarity:
100
91.9
99.5
99.7
N.A.
99.5
99.5
N.A.
86.9
96.5
90.5
92.6
N.A.
73
N.A.
85.2
N.A.
P-Site Identity:
100
86.6
100
93.3
N.A.
100
93.3
N.A.
93.3
86.6
93.3
86.6
N.A.
80
N.A.
80
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
93.3
93.3
93.3
86.6
N.A.
80
N.A.
93.3
N.A.
Percent
Protein Identity:
N.A.
67.9
N.A.
68.9
N.A.
N.A.
Protein Similarity:
N.A.
79.6
N.A.
79.7
N.A.
N.A.
P-Site Identity:
N.A.
53.3
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
N.A.
73.3
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
43
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
100
0
0
0
8
8
0
0
0
0
% D
% Glu:
0
0
0
100
0
0
0
0
0
15
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
15
0
0
0
0
0
93
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
100
0
0
0
% G
% His:
0
0
0
0
0
0
0
29
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
79
0
0
8
0
% K
% Leu:
0
0
0
0
0
0
86
0
0
0
8
0
65
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
86
% R
% Ser:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% S
% Thr:
0
100
0
0
0
0
0
8
93
0
0
0
8
0
0
% T
% Val:
0
0
100
0
100
0
8
0
0
0
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
43
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _