KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANXA5
All Species:
24.55
Human Site:
S146
Identified Species:
60
UniProt:
P08758
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08758
NP_001145.1
320
35937
S146
D
D
V
V
G
D
T
S
G
Y
Y
Q
R
M
L
Chimpanzee
Pan troglodytes
A5A6L7
327
36886
S152
E
D
I
Q
A
D
T
S
G
Y
L
E
R
I
L
Rhesus Macaque
Macaca mulatta
XP_001100224
320
35937
S146
D
D
V
V
G
D
T
S
G
Y
Y
Q
R
M
L
Dog
Lupus familis
XP_533303
321
35925
S146
D
D
V
V
G
D
T
S
G
Y
Y
Q
R
M
L
Cat
Felis silvestris
Mouse
Mus musculus
P48036
319
35734
A164
A
N
R
D
P
D
T
A
I
D
D
A
Q
V
E
Rat
Rattus norvegicus
P14668
319
35726
A164
A
N
R
D
P
D
T
A
I
D
D
A
Q
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513648
322
36187
S146
E
D
V
T
G
D
T
S
G
Y
Y
Q
R
M
L
Chicken
Gallus gallus
P17153
321
36180
S146
D
K
I
T
G
E
T
S
G
H
F
Q
R
L
L
Frog
Xenopus laevis
Q92125
512
53295
S339
K
D
I
R
S
D
T
S
G
H
F
E
R
L
L
Zebra Danio
Brachydanio rerio
NP_861422
317
35042
E148
G
D
T
G
G
H
F
E
R
M
L
A
V
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.8
96.8
97.5
N.A.
93.4
91.8
N.A.
88.5
77.8
29.8
64
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
69.7
98.4
99
N.A.
96.2
95.6
N.A.
94.7
90.3
41.9
79.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
100
100
N.A.
13.3
13.3
N.A.
86.6
53.3
46.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
100
100
N.A.
40
40
N.A.
93.3
86.6
80
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
0
10
0
0
20
0
0
0
30
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
40
70
0
20
0
80
0
0
0
20
20
0
0
0
0
% D
% Glu:
20
0
0
0
0
10
0
10
0
0
0
20
0
0
20
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
20
0
0
0
0
% F
% Gly:
10
0
0
10
60
0
0
0
70
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
20
0
0
0
0
0
% H
% Ile:
0
0
30
0
0
0
0
0
20
0
0
0
0
10
0
% I
% Lys:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
20
0
0
30
80
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
40
0
% M
% Asn:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
50
20
0
0
% Q
% Arg:
0
0
20
10
0
0
0
0
10
0
0
0
70
0
0
% R
% Ser:
0
0
0
0
10
0
0
70
0
0
0
0
0
0
0
% S
% Thr:
0
0
10
20
0
0
90
0
0
0
0
0
0
0
0
% T
% Val:
0
0
40
30
0
0
0
0
0
0
0
0
10
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
50
40
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _