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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYC1
All Species:
22.73
Human Site:
T223
Identified Species:
38.46
UniProt:
P08574
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08574
NP_001907.2
325
35390
T223
T
G
Y
C
E
P
P
T
G
V
S
L
R
E
G
Chimpanzee
Pan troglodytes
XP_528263
468
49840
T366
T
G
Y
C
E
P
P
T
G
V
S
L
R
E
G
Rhesus Macaque
Macaca mulatta
XP_001089897
325
35233
T223
T
G
Y
C
E
P
P
T
G
V
S
L
R
E
G
Dog
Lupus familis
XP_532351
325
35262
T223
T
G
Y
C
E
P
P
T
G
V
S
L
R
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0M3
325
35309
T223
T
G
Y
C
E
P
P
T
G
V
S
L
R
E
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089640
309
34087
A207
T
G
Y
C
D
P
P
A
G
V
T
I
R
E
G
Zebra Danio
Brachydanio rerio
NP_001032470
307
33696
A205
T
G
Y
C
D
P
P
A
G
V
S
L
R
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647958
307
33746
A204
T
G
Y
H
D
A
P
A
G
V
V
L
R
E
G
Honey Bee
Apis mellifera
XP_397047
311
34926
A205
T
G
Y
C
D
P
P
A
G
I
P
I
R
E
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791551
304
33536
A201
T
G
Y
C
E
P
P
A
G
V
E
V
K
G
D
Poplar Tree
Populus trichocarpa
XP_002313590
310
33861
A208
T
G
Y
R
D
P
P
A
G
V
S
I
R
E
G
Maize
Zea mays
NP_001141284
326
35416
T224
T
G
Y
C
E
P
P
T
G
V
S
L
R
E
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07143
309
34036
A204
G
Y
P
D
E
P
P
A
G
V
A
L
P
P
G
Red Bread Mold
Neurospora crassa
P07142
332
36438
A213
G
Y
P
D
E
P
P
A
G
A
S
V
G
A
G
Conservation
Percent
Protein Identity:
100
69.4
94.7
92.3
N.A.
90.7
N.A.
N.A.
N.A.
N.A.
70.4
69.5
N.A.
55
52.9
N.A.
58.4
Protein Similarity:
100
69.4
97.5
94.4
N.A.
94.1
N.A.
N.A.
N.A.
N.A.
82.7
81.8
N.A.
69.8
70.1
N.A.
74.1
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
73.3
86.6
N.A.
66.6
66.6
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
93.3
93.3
N.A.
73.3
86.6
N.A.
73.3
Percent
Protein Identity:
50.7
90.4
N.A.
N.A.
48
48.4
Protein Similarity:
66.4
93.5
N.A.
N.A.
64.3
61.7
P-Site Identity:
73.3
100
N.A.
N.A.
46.6
40
P-Site Similarity:
86.6
100
N.A.
N.A.
53.3
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
58
0
8
8
0
0
8
0
% A
% Cys:
0
0
0
72
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
15
36
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
65
0
0
0
0
0
8
0
0
79
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
15
86
0
0
0
0
0
0
100
0
0
0
8
8
93
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
22
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
65
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
15
0
0
93
100
0
0
0
8
0
8
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
79
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
65
0
0
0
0
% S
% Thr:
86
0
0
0
0
0
0
43
0
0
8
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
86
8
15
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
15
86
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _