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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYC1
All Species:
13.03
Human Site:
S31
Identified Species:
22.05
UniProt:
P08574
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08574
NP_001907.2
325
35390
S31
R
A
R
G
L
L
C
S
A
R
P
G
Q
L
P
Chimpanzee
Pan troglodytes
XP_528263
468
49840
S174
R
A
R
G
L
L
C
S
A
R
P
G
Q
L
P
Rhesus Macaque
Macaca mulatta
XP_001089897
325
35233
S31
R
A
R
G
L
L
C
S
A
R
P
G
Q
L
P
Dog
Lupus familis
XP_532351
325
35262
G31
G
A
R
G
L
L
C
G
A
R
L
G
Q
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0M3
325
35309
G31
S
A
P
G
L
L
G
G
A
R
S
R
Q
L
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089640
309
34087
A36
Q
A
N
V
S
F
S
A
L
S
R
G
R
K
V
Zebra Danio
Brachydanio rerio
NP_001032470
307
33696
S34
R
A
S
M
S
F
A
S
L
P
K
G
K
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647958
307
33746
A31
Q
A
K
N
L
S
S
A
G
S
W
A
S
G
N
Honey Bee
Apis mellifera
XP_397047
311
34926
T31
Q
Q
V
H
N
F
S
T
A
K
Q
W
S
R
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791551
304
33536
A23
S
G
I
L
C
P
K
A
K
L
S
G
F
A
H
Poplar Tree
Populus trichocarpa
XP_002313590
310
33861
T29
T
S
V
L
S
S
F
T
S
K
K
V
H
G
D
Maize
Zea mays
NP_001141284
326
35416
G32
S
A
P
G
L
L
G
G
A
R
P
R
H
L
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07143
309
34036
A26
Y
S
T
A
T
G
A
A
S
K
S
G
K
L
T
Red Bread Mold
Neurospora crassa
P07142
332
36438
F23
A
K
N
G
A
F
K
F
A
K
R
S
A
S
T
Conservation
Percent
Protein Identity:
100
69.4
94.7
92.3
N.A.
90.7
N.A.
N.A.
N.A.
N.A.
70.4
69.5
N.A.
55
52.9
N.A.
58.4
Protein Similarity:
100
69.4
97.5
94.4
N.A.
94.1
N.A.
N.A.
N.A.
N.A.
82.7
81.8
N.A.
69.8
70.1
N.A.
74.1
P-Site Identity:
100
100
100
80
N.A.
60
N.A.
N.A.
N.A.
N.A.
13.3
26.6
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
80
N.A.
60
N.A.
N.A.
N.A.
N.A.
33.3
33.3
N.A.
33.3
26.6
N.A.
13.3
Percent
Protein Identity:
50.7
90.4
N.A.
N.A.
48
48.4
Protein Similarity:
66.4
93.5
N.A.
N.A.
64.3
61.7
P-Site Identity:
0
60
N.A.
N.A.
13.3
13.3
P-Site Similarity:
26.6
60
N.A.
N.A.
46.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
65
0
8
8
0
15
29
58
0
0
8
8
8
0
% A
% Cys:
0
0
0
0
8
0
29
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
29
8
8
0
0
0
0
8
0
0
% F
% Gly:
8
8
0
50
0
8
15
22
8
0
0
58
0
15
8
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
15
0
8
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
8
8
0
0
0
15
0
8
29
15
0
15
15
0
% K
% Leu:
0
0
0
15
50
43
0
0
15
8
8
0
0
50
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
15
8
8
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
15
0
0
8
0
0
0
8
29
0
0
0
43
% P
% Gln:
22
8
0
0
0
0
0
0
0
0
8
0
36
0
0
% Q
% Arg:
29
0
29
0
0
0
0
0
0
43
15
15
8
8
0
% R
% Ser:
22
15
8
0
22
15
22
29
15
15
22
8
15
8
0
% S
% Thr:
8
0
8
0
8
0
0
15
0
0
0
0
0
0
15
% T
% Val:
0
0
15
8
0
0
0
0
0
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _