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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MMP2 All Species: 39.09
Human Site: S644 Identified Species: 86
UniProt: P08253 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08253 NP_001121363.1 660 73882 S644 Y L K L E N Q S L K S V K F G
Chimpanzee Pan troglodytes XP_001167520 660 73986 S644 Y L K L E N Q S L K S V K F G
Rhesus Macaque Macaca mulatta XP_001087939 660 73880 S644 Y L K L E N Q S L K S V K F G
Dog Lupus familis XP_535300 612 68986 S596 Y L K L E N Q S L K S V K F G
Cat Felis silvestris
Mouse Mus musculus P33434 662 74084 S646 Y L K L E N Q S L K S V K F G
Rat Rattus norvegicus P33436 662 74131 S646 Y L K L E N Q S L K S V K F G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508394 704 78508 S688 Y L K M E D K S L K I V K V G
Chicken Gallus gallus Q90611 663 74923 S647 Y L Q M E D K S L K I V K I G
Frog Xenopus laevis O13065 467 52794 S452 Q F E Y N I N S K R I V Q V L
Zebra Danio Brachydanio rerio NP_932333 657 74257 T641 Y L K M D D S T L K I I K V G
Tiger Blowfish Takifugu rubipres NP_001032958 658 74198 S642 Y F K L E D N S L K I V K L G
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.1 99.6 89.8 N.A. 95.6 95.1 N.A. 81.5 82.1 31.6 71.8 71.8 N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.1 99.8 91.6 N.A. 97.4 97.1 N.A. 88.6 90.3 42.8 83.3 81.9 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 66.6 60 13.3 46.6 66.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 86.6 86.6 33.3 80 73.3 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 37 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 82 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 19 0 0 0 0 0 0 0 0 0 0 0 55 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 91 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 46 10 0 10 0 % I
% Lys: 0 0 82 0 0 0 19 0 10 91 0 0 91 0 0 % K
% Leu: 0 82 0 64 0 0 0 0 91 0 0 0 0 10 10 % L
% Met: 0 0 0 28 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 55 19 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 0 10 0 0 0 55 0 0 0 0 0 10 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 10 91 0 0 55 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 91 0 28 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 91 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _