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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRPR All Species: 18.18
Human Site: S473 Identified Species: 30.77
UniProt: P08240 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08240 NP_003130.2 638 69811 S473 R T H T R R L S A L H P P E K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112588 638 69763 S473 R T H T R R L S A L H P P E K
Dog Lupus familis XP_546411 612 66844 S447 R T H T R R L S A L H P P E K
Cat Felis silvestris
Mouse Mus musculus Q9DBG7 636 69604 T471 R T H T R R L T A L H P P E K
Rat Rattus norvegicus NP_001029322 636 69638 T471 R T H T R R L T A L H P P E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001034366 644 71178 N479 R T H T R R L N A L H P P E S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_697518 650 71144 N485 R T H Q R R L N S L H P P E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U5L1 614 67777 N450 R T H T R H L N A L H P A A K
Honey Bee Apis mellifera XP_395013 605 68213 N441 R T H M R H L N A L H P P E K
Nematode Worm Caenorhab. elegans NP_741303 625 69292 N467 R T H A R Y L N D L H K N S V
Sea Urchin Strong. purpuratus XP_001188635 584 65767 A449 C D T F R A G A V E Q L R T H
Poplar Tree Populus trichocarpa XP_002309350 624 68615 Q473 R T H A R R L Q I P I F E K G
Maize Zea mays NP_001130574 625 68471 Q474 R T H A R R L Q I P I F E K G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32916 621 69260 A452 R V H V E N L A Q L M D D S H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.5 92.9 N.A. 97.1 97.6 N.A. N.A. 78.7 N.A. 67.3 N.A. 51.4 58.1 49 52.8
Protein Similarity: 100 N.A. 99.6 93.7 N.A. 98.2 98.7 N.A. N.A. 87.4 N.A. 78.7 N.A. 69.7 71.6 66.1 63.9
P-Site Identity: 100 N.A. 100 100 N.A. 93.3 93.3 N.A. N.A. 86.6 N.A. 80 N.A. 73.3 80 46.6 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. 93.3 N.A. 93.3 N.A. 80 86.6 53.3 13.3
Percent
Protein Identity: 43.2 43.7 N.A. N.A. 31.6 N.A.
Protein Similarity: 59.5 61.1 N.A. N.A. 51.7 N.A.
P-Site Identity: 40 40 N.A. N.A. 26.6 N.A.
P-Site Similarity: 46.6 46.6 N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 22 0 8 0 15 58 0 0 0 8 8 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 8 0 0 8 8 0 0 % D
% Glu: 0 0 0 0 8 0 0 0 0 8 0 0 15 58 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 15 0 0 0 % F
% Gly: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 15 % G
% His: 0 0 93 0 0 15 0 0 0 0 72 0 0 0 15 % H
% Ile: 0 0 0 0 0 0 0 0 15 0 15 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 8 0 15 58 % K
% Leu: 0 0 0 0 0 0 93 0 0 79 0 8 0 0 0 % L
% Met: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 36 0 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 15 0 65 58 0 0 % P
% Gln: 0 0 0 8 0 0 0 15 8 0 8 0 0 0 0 % Q
% Arg: 93 0 0 0 93 65 0 0 0 0 0 0 8 0 0 % R
% Ser: 0 0 0 0 0 0 0 22 8 0 0 0 0 15 8 % S
% Thr: 0 86 8 50 0 0 0 15 0 0 0 0 0 8 0 % T
% Val: 0 8 0 8 0 0 0 0 8 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _