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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPR
All Species:
22.12
Human Site:
S296
Identified Species:
37.44
UniProt:
P08240
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08240
NP_003130.2
638
69811
S296
Q
L
Q
D
L
D
C
S
S
S
D
D
E
G
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112588
638
69763
S296
Q
L
Q
D
L
D
C
S
S
S
D
D
E
G
A
Dog
Lupus familis
XP_546411
612
66844
S270
Q
L
Q
D
L
D
C
S
S
S
D
D
E
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBG7
636
69604
S295
Q
L
Q
D
L
D
C
S
S
S
D
D
E
G
A
Rat
Rattus norvegicus
NP_001029322
636
69638
S295
Q
L
Q
D
L
D
C
S
S
S
D
D
E
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001034366
644
71178
E302
D
L
E
Y
E
S
D
E
E
A
E
E
E
K
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697518
650
71144
E308
D
D
E
D
E
E
V
E
E
E
E
K
K
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U5L1
614
67777
D273
V
E
S
E
D
E
A
D
N
E
D
A
S
S
E
Honey Bee
Apis mellifera
XP_395013
605
68213
V274
E
D
E
S
D
E
E
V
E
N
S
K
S
Q
M
Nematode Worm
Caenorhab. elegans
NP_741303
625
69292
K290
G
T
L
K
G
D
L
K
S
L
Q
E
S
D
D
Sea Urchin
Strong. purpuratus
XP_001188635
584
65767
E284
E
E
E
E
E
E
E
E
E
E
V
E
V
K
K
Poplar Tree
Populus trichocarpa
XP_002309350
624
68615
S296
D
K
E
E
I
V
S
S
D
S
E
D
E
E
D
Maize
Zea mays
NP_001130574
625
68471
E307
E
D
L
S
S
D
S
E
D
E
E
V
E
D
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32916
621
69260
S279
S
H
K
D
E
I
T
S
G
N
E
A
K
N
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.5
92.9
N.A.
97.1
97.6
N.A.
N.A.
78.7
N.A.
67.3
N.A.
51.4
58.1
49
52.8
Protein Similarity:
100
N.A.
99.6
93.7
N.A.
98.2
98.7
N.A.
N.A.
87.4
N.A.
78.7
N.A.
69.7
71.6
66.1
63.9
P-Site Identity:
100
N.A.
100
86.6
N.A.
100
100
N.A.
N.A.
13.3
N.A.
6.6
N.A.
6.6
0
13.3
0
P-Site Similarity:
100
N.A.
100
86.6
N.A.
100
100
N.A.
N.A.
40
N.A.
33.3
N.A.
26.6
26.6
20
33.3
Percent
Protein Identity:
43.2
43.7
N.A.
N.A.
31.6
N.A.
Protein Similarity:
59.5
61.1
N.A.
N.A.
51.7
N.A.
P-Site Identity:
26.6
13.3
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
53.3
26.6
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
8
0
15
0
0
29
% A
% Cys:
0
0
0
0
0
0
36
0
0
0
0
0
0
0
0
% C
% Asp:
22
22
0
50
15
50
8
8
15
0
43
43
0
15
15
% D
% Glu:
22
15
36
22
29
29
15
29
29
29
36
22
58
15
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
8
0
0
0
8
0
0
0
0
29
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
8
8
8
0
0
0
8
0
0
0
15
15
15
8
% K
% Leu:
0
43
15
0
36
0
8
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
8
15
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
36
0
36
0
0
0
0
0
0
0
8
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
8
15
8
8
15
50
43
43
8
0
22
8
8
% S
% Thr:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
8
% T
% Val:
8
0
0
0
0
8
8
8
0
0
8
8
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _