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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPR
All Species:
14.55
Human Site:
S275
Identified Species:
24.62
UniProt:
P08240
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08240
NP_003130.2
638
69811
S275
G
T
P
E
A
A
L
S
E
D
I
N
L
I
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112588
638
69763
S275
G
S
P
E
A
A
L
S
E
D
I
N
L
I
R
Dog
Lupus familis
XP_546411
612
66844
P249
G
A
P
D
A
A
P
P
E
D
I
N
L
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBG7
636
69604
S274
G
T
P
E
A
A
L
S
E
D
I
N
L
I
R
Rat
Rattus norvegicus
NP_001029322
636
69638
S274
G
T
P
E
A
A
L
S
E
D
I
N
L
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001034366
644
71178
M281
M
E
D
F
D
P
D
M
A
L
R
D
R
N
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697518
650
71144
S287
E
P
A
I
Q
V
E
S
M
K
G
D
L
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U5L1
614
67777
E252
Q
Y
Q
N
I
N
S
E
L
V
G
T
M
Q
G
Honey Bee
Apis mellifera
XP_395013
605
68213
M253
D
K
T
L
V
G
K
M
K
G
G
I
R
D
I
Nematode Worm
Caenorhab. elegans
NP_741303
625
69292
E269
N
D
E
N
A
A
D
E
E
K
N
R
F
V
E
Sea Urchin
Strong. purpuratus
XP_001188635
584
65767
K263
S
A
W
V
G
T
M
K
G
E
L
P
N
I
D
Poplar Tree
Populus trichocarpa
XP_002309350
624
68615
N275
V
E
G
N
G
N
E
N
I
E
V
V
A
A
D
Maize
Zea mays
NP_001130574
625
68471
N286
R
G
D
E
V
A
D
N
V
A
V
I
E
G
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32916
621
69260
G258
S
F
G
D
R
T
E
G
G
D
F
L
I
K
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.5
92.9
N.A.
97.1
97.6
N.A.
N.A.
78.7
N.A.
67.3
N.A.
51.4
58.1
49
52.8
Protein Similarity:
100
N.A.
99.6
93.7
N.A.
98.2
98.7
N.A.
N.A.
87.4
N.A.
78.7
N.A.
69.7
71.6
66.1
63.9
P-Site Identity:
100
N.A.
93.3
73.3
N.A.
100
100
N.A.
N.A.
6.6
N.A.
13.3
N.A.
0
0
20
6.6
P-Site Similarity:
100
N.A.
100
80
N.A.
100
100
N.A.
N.A.
13.3
N.A.
20
N.A.
6.6
6.6
26.6
26.6
Percent
Protein Identity:
43.2
43.7
N.A.
N.A.
31.6
N.A.
Protein Similarity:
59.5
61.1
N.A.
N.A.
51.7
N.A.
P-Site Identity:
0
13.3
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
20
26.6
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
8
0
43
50
0
0
8
8
0
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
15
15
8
0
22
0
0
43
0
15
0
8
15
% D
% Glu:
8
15
8
36
0
0
22
15
43
15
0
0
8
0
22
% E
% Phe:
0
8
0
8
0
0
0
0
0
0
8
0
8
0
0
% F
% Gly:
36
8
15
0
15
8
0
8
15
8
22
0
0
8
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
8
0
0
0
8
0
36
15
8
43
8
% I
% Lys:
0
8
0
0
0
0
8
8
8
15
0
0
0
8
0
% K
% Leu:
0
0
0
8
0
0
29
0
8
8
8
8
43
0
0
% L
% Met:
8
0
0
0
0
0
8
15
8
0
0
0
8
0
0
% M
% Asn:
8
0
0
22
0
15
0
15
0
0
8
36
8
8
0
% N
% Pro:
0
8
36
0
0
8
8
8
0
0
0
8
0
0
0
% P
% Gln:
8
0
8
0
8
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
8
0
0
0
8
0
0
0
0
0
8
8
15
8
43
% R
% Ser:
15
8
0
0
0
0
8
36
0
0
0
0
0
0
0
% S
% Thr:
0
22
8
0
0
15
0
0
0
0
0
8
0
0
0
% T
% Val:
8
0
0
8
15
8
0
0
8
8
15
8
0
8
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _