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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPR
All Species:
24.55
Human Site:
S127
Identified Species:
41.54
UniProt:
P08240
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08240
NP_003130.2
638
69811
S127
L
L
R
E
A
E
E
S
S
K
I
R
A
P
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112588
638
69763
S127
L
L
R
E
A
E
E
S
S
K
I
R
A
P
T
Dog
Lupus familis
XP_546411
612
66844
K121
E
D
S
E
K
A
K
K
P
V
R
S
M
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBG7
636
69604
S127
L
L
R
E
A
E
E
S
S
K
I
R
A
P
T
Rat
Rattus norvegicus
NP_001029322
636
69638
S127
L
L
R
E
A
E
E
S
S
K
I
R
A
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001034366
644
71178
S130
L
L
R
E
A
E
E
S
S
K
V
R
A
P
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697518
650
71144
S129
L
L
R
E
A
E
E
S
S
K
A
K
G
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U5L1
614
67777
A122
S
A
A
E
E
A
S
A
K
Q
V
K
A
P
K
Honey Bee
Apis mellifera
XP_395013
605
68213
R125
T
M
A
E
Q
W
A
R
T
Q
A
K
I
P
K
Nematode Worm
Caenorhab. elegans
NP_741303
625
69292
S130
V
L
S
E
A
A
K
S
A
R
A
T
E
N
T
Sea Urchin
Strong. purpuratus
XP_001188635
584
65767
Q130
V
V
A
K
K
G
K
Q
M
K
S
F
E
E
S
Poplar Tree
Populus trichocarpa
XP_002309350
624
68615
L143
G
V
N
D
G
R
K
L
V
M
K
K
G
S
G
Maize
Zea mays
NP_001130574
625
68471
G146
A
L
T
Q
K
K
P
G
P
K
G
R
G
G
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32916
621
69260
I122
S
L
H
L
S
E
S
I
L
K
N
R
Q
G
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.5
92.9
N.A.
97.1
97.6
N.A.
N.A.
78.7
N.A.
67.3
N.A.
51.4
58.1
49
52.8
Protein Similarity:
100
N.A.
99.6
93.7
N.A.
98.2
98.7
N.A.
N.A.
87.4
N.A.
78.7
N.A.
69.7
71.6
66.1
63.9
P-Site Identity:
100
N.A.
100
6.6
N.A.
100
100
N.A.
N.A.
93.3
N.A.
73.3
N.A.
20
13.3
33.3
6.6
P-Site Similarity:
100
N.A.
100
13.3
N.A.
100
100
N.A.
N.A.
100
N.A.
80
N.A.
46.6
40
60
40
Percent
Protein Identity:
43.2
43.7
N.A.
N.A.
31.6
N.A.
Protein Similarity:
59.5
61.1
N.A.
N.A.
51.7
N.A.
P-Site Identity:
0
20
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
26.6
33.3
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
22
0
50
22
8
8
8
0
22
0
43
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
8
0
0
72
8
50
43
0
0
0
0
0
15
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
8
0
0
0
8
8
0
8
0
0
8
0
22
15
8
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
29
0
8
8
0
% I
% Lys:
0
0
0
8
22
8
29
8
8
65
8
29
0
0
15
% K
% Leu:
43
65
0
8
0
0
0
8
8
0
0
0
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
8
8
0
0
8
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
8
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
8
0
15
0
0
0
0
58
0
% P
% Gln:
0
0
0
8
8
0
0
8
0
15
0
0
8
0
8
% Q
% Arg:
0
0
43
0
0
8
0
8
0
8
8
50
0
0
0
% R
% Ser:
15
0
15
0
8
0
15
50
43
0
8
8
0
8
8
% S
% Thr:
8
0
8
0
0
0
0
0
8
0
0
8
0
0
43
% T
% Val:
15
15
0
0
0
0
0
0
8
8
15
0
0
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _