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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPINA6
All Species:
9.09
Human Site:
S122
Identified Species:
28.57
UniProt:
P08185
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08185
NP_001747.2
405
45141
S122
L
F
A
K
S
D
T
S
L
E
M
T
M
G
N
Chimpanzee
Pan troglodytes
XP_510143
405
44978
S122
L
F
A
K
S
D
T
S
L
E
M
T
M
G
N
Rhesus Macaque
Macaca mulatta
XP_001098128
404
44725
S122
L
F
A
E
S
D
T
S
L
E
M
T
M
G
N
Dog
Lupus familis
XP_547960
404
45458
M121
L
L
E
K
S
D
T
M
L
E
M
T
M
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q06770
397
44751
N122
G
L
E
M
N
M
G
N
V
M
F
L
L
Q
N
Rat
Rattus norvegicus
P31211
396
44652
N121
G
L
E
M
N
M
G
N
A
M
F
L
L
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516508
456
51272
D166
T
L
N
L
T
S
N
D
L
E
I
N
M
G
N
Chicken
Gallus gallus
XP_421343
376
43112
Q104
I
D
E
R
L
K
L
Q
Q
K
F
L
D
D
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
93.3
69.6
N.A.
57.5
60.7
N.A.
42.7
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
95.8
80.7
N.A.
73.3
76.3
N.A.
60
60.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
6.6
0
N.A.
33.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
33.3
20
N.A.
46.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
38
0
0
0
0
0
13
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
0
0
0
50
0
13
0
0
0
0
13
13
0
% D
% Glu:
0
0
50
13
0
0
0
0
0
63
0
0
0
0
0
% E
% Phe:
0
38
0
0
0
0
0
0
0
0
38
0
0
0
0
% F
% Gly:
25
0
0
0
0
0
25
0
0
0
0
0
0
63
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% I
% Lys:
0
0
0
38
0
13
0
0
0
13
0
0
0
0
13
% K
% Leu:
50
50
0
13
13
0
13
0
63
0
0
38
25
0
0
% L
% Met:
0
0
0
25
0
25
0
13
0
25
50
0
63
0
0
% M
% Asn:
0
0
13
0
25
0
13
25
0
0
0
13
0
0
75
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
13
13
0
0
0
0
25
0
% Q
% Arg:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
50
13
0
38
0
0
0
0
0
0
0
% S
% Thr:
13
0
0
0
13
0
50
0
0
0
0
50
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _