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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FH
All Species:
36.06
Human Site:
Y110
Identified Species:
66.11
UniProt:
P07954
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07954
NP_000134.2
510
54637
Y110
A
A
E
V
N
Q
D
Y
G
L
D
P
K
I
A
Chimpanzee
Pan troglodytes
XP_001160068
510
54605
Y110
A
A
E
V
N
Q
D
Y
G
L
D
P
K
I
A
Rhesus Macaque
Macaca mulatta
XP_001094968
510
54694
Y110
A
A
E
V
N
Q
D
Y
G
L
D
P
K
I
A
Dog
Lupus familis
XP_537215
508
54433
Y108
A
A
E
V
N
Q
D
Y
G
L
D
S
K
I
A
Cat
Felis silvestris
Mouse
Mus musculus
P97807
507
54352
Y107
A
A
E
V
N
Q
E
Y
G
L
D
P
K
I
A
Rat
Rattus norvegicus
P14408
507
54445
Y107
A
A
E
V
N
Q
E
Y
G
L
D
P
K
I
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514191
558
58974
Y158
A
A
E
V
N
Q
D
Y
G
L
D
P
K
I
A
Chicken
Gallus gallus
NP_001006382
507
54281
Y107
A
A
E
V
N
Q
D
Y
G
L
D
P
K
I
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SX99
509
54842
Y109
A
A
E
V
N
K
D
Y
G
L
D
P
K
I
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572339
495
53557
D110
A
I
S
K
A
A
D
D
V
I
S
G
K
L
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17214
501
53628
E117
A
I
S
Q
A
A
D
E
V
V
D
G
K
L
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FI53
499
54065
A108
L
D
P
M
I
G
E
A
I
M
E
A
A
Q
E
Baker's Yeast
Sacchar. cerevisiae
P08417
488
53133
A107
Q
Q
A
A
D
E
V
A
S
G
K
L
D
D
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.4
95.2
N.A.
92.9
92.7
N.A.
80.6
86.4
N.A.
82.5
N.A.
72.9
N.A.
71.3
N.A.
Protein Similarity:
100
99.6
99
97.2
N.A.
95.4
94.5
N.A.
84.9
92.9
N.A.
89.4
N.A.
82.9
N.A.
81.5
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
100
100
N.A.
93.3
N.A.
20
N.A.
26.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
33.3
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
65.2
62.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
76.8
75.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
85
70
8
8
16
16
0
16
0
0
0
8
8
0
70
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
0
70
8
0
0
77
0
8
8
8
% D
% Glu:
0
0
70
0
0
8
24
8
0
0
8
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
70
8
0
16
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
16
0
0
8
0
0
0
8
8
0
0
0
70
0
% I
% Lys:
0
0
0
8
0
8
0
0
0
0
8
0
85
0
0
% K
% Leu:
8
0
0
0
0
0
0
0
0
70
0
8
0
16
0
% L
% Met:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
70
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
62
0
0
0
% P
% Gln:
8
8
0
8
0
62
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
16
0
0
0
0
0
8
0
8
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
70
0
0
8
0
16
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _