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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FH All Species: 54.55
Human Site: S366 Identified Species: 100
UniProt: P07954 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P07954 NP_000134.2 510 54637 S366 P E N E P G S S I M P G K V N
Chimpanzee Pan troglodytes XP_001160068 510 54605 S366 P E N E P G S S I M P G K V N
Rhesus Macaque Macaca mulatta XP_001094968 510 54694 S366 P E N E P G S S I M P G K V N
Dog Lupus familis XP_537215 508 54433 S364 P E N E P G S S I M P G K V N
Cat Felis silvestris
Mouse Mus musculus P97807 507 54352 S363 P E N E P G S S I M P G K V N
Rat Rattus norvegicus P14408 507 54445 S363 P E N E P G S S I M P G K V N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514191 558 58974 S414 P E N E P G S S I M P G K V N
Chicken Gallus gallus NP_001006382 507 54281 S363 P E N E P G S S I M P G K V N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7SX99 509 54842 S365 P E N E P G S S I M P G K V N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572339 495 53557 S351 P E N E P G S S I M P G K V N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O17214 501 53628 S357 P E N E P G S S I M P G K V N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FI53 499 54065 S354 P E N E P G S S I M P G K V N
Baker's Yeast Sacchar. cerevisiae P08417 488 53133 S344 P E N E P G S S I M P G K V N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.4 95.2 N.A. 92.9 92.7 N.A. 80.6 86.4 N.A. 82.5 N.A. 72.9 N.A. 71.3 N.A.
Protein Similarity: 100 99.6 99 97.2 N.A. 95.4 94.5 N.A. 84.9 92.9 N.A. 89.4 N.A. 82.9 N.A. 81.5 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 N.A. 100 N.A. 100 N.A. 100 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 N.A. 100 N.A. 100 N.A. 100 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 65.2 62.7 N.A.
Protein Similarity: N.A. N.A. N.A. 76.8 75.6 N.A.
P-Site Identity: N.A. N.A. N.A. 100 100 N.A.
P-Site Similarity: N.A. N.A. N.A. 100 100 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 100 0 100 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 100 0 0 0 0 0 100 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % M
% Asn: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 100 % N
% Pro: 100 0 0 0 100 0 0 0 0 0 100 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 100 100 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _