KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LAMB1
All Species:
27.27
Human Site:
Y194
Identified Species:
46.15
UniProt:
P07942
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07942
NP_002282.2
1786
198066
Y194
D
I
I
C
D
S
R
Y
S
D
I
E
P
S
T
Chimpanzee
Pan troglodytes
XP_001165635
1786
198155
Y194
D
I
I
C
D
S
R
Y
S
D
I
E
P
S
T
Rhesus Macaque
Macaca mulatta
XP_001090393
1960
216360
Y368
D
I
I
C
D
S
R
Y
S
D
I
E
P
S
T
Dog
Lupus familis
XP_533089
1655
182573
L176
C
R
H
N
T
K
G
L
N
C
E
Q
C
M
D
Cat
Felis silvestris
Mouse
Mus musculus
P02469
1786
196886
Y194
D
I
I
C
D
S
R
Y
S
D
I
E
P
S
T
Rat
Rattus norvegicus
P15800
1801
196455
Y209
D
V
V
C
E
S
R
Y
S
E
I
E
P
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506672
1850
202794
F190
S
S
Q
G
E
V
I
F
K
V
L
D
P
A
I
Chicken
Gallus gallus
XP_415943
2147
234237
D556
I
C
D
S
R
Y
S
D
I
E
P
S
T
E
G
Frog
Xenopus laevis
NP_001088164
1783
197665
Y194
D
V
I
C
E
S
R
Y
S
D
I
E
P
S
T
Zebra Danio
Brachydanio rerio
Q8JHV6
1827
203534
A192
C
D
S
R
Y
S
G
A
E
P
S
T
E
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P11046
1788
198315
S212
V
M
C
T
S
R
Y
S
N
V
E
P
S
R
N
Honey Bee
Apis mellifera
XP_001122457
1816
202931
Y244
D
V
I
C
E
S
R
Y
S
G
V
A
P
S
T
Nematode Worm
Caenorhab. elegans
Q18823
1535
170219
G56
V
Q
V
T
N
T
C
G
T
K
R
P
T
K
F
Sea Urchin
Strong. purpuratus
XP_001195934
1658
183520
E179
N
I
S
Q
V
I
C
E
S
R
Y
S
A
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
90.1
85.3
N.A.
92.6
50.7
N.A.
42.2
66.5
55.3
39.9
N.A.
40.8
42
26.9
43.5
Protein Similarity:
100
99.7
90.7
89.5
N.A.
96.6
67.9
N.A.
59.1
74.3
72.6
57.5
N.A.
60
58.9
44.2
60.3
P-Site Identity:
100
100
100
0
N.A.
100
73.3
N.A.
6.6
0
86.6
6.6
N.A.
0
66.6
0
13.3
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
40
6.6
100
6.6
N.A.
13.3
86.6
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
0
8
8
8
0
% A
% Cys:
15
8
8
50
0
0
15
0
0
8
0
0
8
0
0
% C
% Asp:
50
8
8
0
29
0
0
8
0
36
0
8
0
0
8
% D
% Glu:
0
0
0
0
29
0
0
8
8
15
15
43
8
8
15
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
8
0
0
15
8
0
8
0
0
0
8
8
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
36
43
0
0
8
8
0
8
0
43
0
0
0
8
% I
% Lys:
0
0
0
0
0
8
0
0
8
8
0
0
0
8
0
% K
% Leu:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
0
0
8
8
0
0
0
15
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
8
15
58
0
0
% P
% Gln:
0
8
8
8
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
8
0
8
8
8
50
0
0
8
8
0
0
8
0
% R
% Ser:
8
8
15
8
8
58
8
8
58
0
8
15
8
50
0
% S
% Thr:
0
0
0
15
8
8
0
0
8
0
0
8
15
0
50
% T
% Val:
15
22
15
0
8
8
0
0
0
15
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
8
8
50
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _