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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSL1
All Species:
27.88
Human Site:
Y204
Identified Species:
68.15
UniProt:
P07711
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07711
NP_001903.1
333
37564
Y204
D
S
E
E
S
Y
P
Y
E
A
T
E
E
S
C
Chimpanzee
Pan troglodytes
XP_001137800
299
33813
E174
S
Y
P
Y
E
A
T
E
E
S
C
K
Y
N
P
Rhesus Macaque
Macaca mulatta
XP_001086024
333
37445
Y204
D
S
E
E
S
Y
P
Y
E
A
T
E
E
S
C
Dog
Lupus familis
XP_541257
333
37479
Y204
D
S
E
E
S
Y
P
Y
L
A
R
N
E
P
C
Cat
Felis silvestris
Mouse
Mus musculus
P06797
334
37529
Y204
D
S
E
E
S
Y
P
Y
E
A
K
D
G
S
C
Rat
Rattus norvegicus
P07154
334
37642
Y204
D
S
E
E
S
Y
P
Y
E
A
K
D
G
S
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P09648
218
23945
T92
S
E
E
S
Y
P
Y
T
A
K
D
D
E
D
C
Frog
Xenopus laevis
NP_001087489
335
37630
Y204
D
S
E
D
S
Y
P
Y
T
A
K
D
D
Q
E
Zebra Danio
Brachydanio rerio
NP_997749
337
38399
Y206
D
S
E
E
S
Y
P
Y
L
G
T
D
D
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95029
371
41582
Y244
D
T
E
K
S
Y
P
Y
E
A
I
D
D
S
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.7
96.4
69.3
N.A.
71.8
73
N.A.
N.A.
51.3
65
65.2
N.A.
49.5
N.A.
N.A.
N.A.
Protein Similarity:
100
89.7
98.8
81.6
N.A.
85.9
86.2
N.A.
N.A.
57.9
79
76.8
N.A.
64.1
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
73.3
N.A.
80
80
N.A.
N.A.
20
53.3
60
N.A.
66.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
73.3
N.A.
86.6
86.6
N.A.
N.A.
26.6
73.3
73.3
N.A.
93.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
10
70
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
70
% C
% Asp:
80
0
0
10
0
0
0
0
0
0
10
60
30
10
0
% D
% Glu:
0
10
90
60
10
0
0
10
60
0
0
20
40
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
0
20
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
10
30
10
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% N
% Pro:
0
0
10
0
0
10
80
0
0
0
0
0
0
10
20
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
20
70
0
10
80
0
0
0
0
10
0
0
0
50
0
% S
% Thr:
0
10
0
0
0
0
10
10
10
0
30
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
10
10
80
10
80
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _