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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADRB2 All Species: 30.3
Human Site: Y219 Identified Species: 66.67
UniProt: P07550 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P07550 NP_000015.1 413 46427 Y219 L V I M V F V Y S R V F Q E A
Chimpanzee Pan troglodytes XP_527068 720 79546 Y526 L V I M V F V Y S R V F Q E A
Rhesus Macaque Macaca mulatta Q28509 415 46453 Y219 L V I M V F V Y S R V F Q E A
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P18762 418 46984 Y219 L C V M V F V Y S R V F Q V A
Rat Rattus norvegicus P10608 418 46873 Y219 L V V M V F V Y S R V F Q V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513543 477 52086 Y235 L A V M A F V Y L R V F R E A
Chicken Gallus gallus XP_425195 397 44745 Y216 L V V M V F V Y A R V F Q V A
Frog Xenopus laevis O42574 385 43291 S207 R A Y A I A S S I I S F Y F P
Zebra Danio Brachydanio rerio NP_001096122 405 46098 Y214 L V I M V F V Y S R V F Q E A
Tiger Blowfish Takifugu rubipres P53452 459 51062 A209 I S F Y I P V A I M I V T Y T
Fruit Fly Dros. melanogaster Q4LBB9 536 60360 L339 T I M I F T Y L A I F R E A N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 57 97.5 N.A. N.A. 86.8 87.3 N.A. 45.7 70.9 51.3 54.4 33.9 30.7 N.A. N.A. N.A.
Protein Similarity: 100 57.2 98.3 N.A. N.A. 91.1 91.6 N.A. 58.7 79.6 65.3 70.4 50.7 44.4 N.A. N.A. N.A.
P-Site Identity: 100 100 100 N.A. N.A. 80 86.6 N.A. 66.6 80 6.6 100 6.6 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 86.6 93.3 N.A. 80 93.3 13.3 100 26.6 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 0 10 10 10 0 10 19 0 0 0 0 10 73 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 10 46 0 % E
% Phe: 0 0 10 0 10 73 0 0 0 0 10 82 0 10 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 10 37 10 19 0 0 0 19 19 10 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 73 0 0 0 0 0 0 10 10 0 0 0 0 0 0 % L
% Met: 0 0 10 73 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 64 0 0 % Q
% Arg: 10 0 0 0 0 0 0 0 0 73 0 10 10 0 0 % R
% Ser: 0 10 0 0 0 0 10 10 55 0 10 0 0 0 0 % S
% Thr: 10 0 0 0 0 10 0 0 0 0 0 0 10 0 10 % T
% Val: 0 55 37 0 64 0 82 0 0 0 73 10 0 28 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 10 0 0 10 73 0 0 0 0 10 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _