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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRP All Species: 9.09
Human Site: S60 Identified Species: 25
UniProt: P07492 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P07492 NP_001012530.1 148 16144 S60 K S T G E S S S V S E R G S L
Chimpanzee Pan troglodytes XP_001142106 148 16210 S60 K S T G E S S S V S E R G S L
Rhesus Macaque Macaca mulatta XP_001087091 112 12229 Q47 A K E N R N H Q P P Q P K A L
Dog Lupus familis XP_866119 140 15382 S65 R V P G S R R S L S S L G L P
Cat Felis silvestris
Mouse Mus musculus Q8R1I2 146 15640 Y64 T D E S P S L Y A A D R D G L
Rat Rattus norvegicus P24393 147 15798 Y64 T D E L P P L Y A A D R D G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511056 98 11329 R36 K Q L S E Y L R W E E T A K N
Chicken Gallus gallus
Frog Xenopus laevis P43443 120 14365 H52 G N Q W A I G H F M G K K S L
Zebra Danio Brachydanio rerio NP_001154822 153 17802 I60 K S T D D Q D I S E D S N D D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 63.5 32.4 N.A. 59.4 60.8 N.A. 25.6 N.A. 23.6 24.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.6 64.8 45.9 N.A. 71.6 70.9 N.A. 44.5 N.A. 41.8 41.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 26.6 N.A. 20 13.3 N.A. 20 N.A. 13.3 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 40 N.A. 33.3 26.6 N.A. 20 N.A. 26.6 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 0 12 0 0 0 23 23 0 0 12 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 23 0 12 12 0 12 0 0 0 34 0 23 12 12 % D
% Glu: 0 0 34 0 34 0 0 0 0 23 34 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % F
% Gly: 12 0 0 34 0 0 12 0 0 0 12 0 34 23 0 % G
% His: 0 0 0 0 0 0 12 12 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 12 0 12 0 0 0 0 0 0 0 % I
% Lys: 45 12 0 0 0 0 0 0 0 0 0 12 23 12 0 % K
% Leu: 0 0 12 12 0 0 34 0 12 0 0 12 0 12 67 % L
% Met: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % M
% Asn: 0 12 0 12 0 12 0 0 0 0 0 0 12 0 12 % N
% Pro: 0 0 12 0 23 12 0 0 12 12 0 12 0 0 12 % P
% Gln: 0 12 12 0 0 12 0 12 0 0 12 0 0 0 0 % Q
% Arg: 12 0 0 0 12 12 12 12 0 0 0 45 0 0 0 % R
% Ser: 0 34 0 23 12 34 23 34 12 34 12 12 0 34 0 % S
% Thr: 23 0 34 0 0 0 0 0 0 0 0 12 0 0 0 % T
% Val: 0 12 0 0 0 0 0 0 23 0 0 0 0 0 0 % V
% Trp: 0 0 0 12 0 0 0 0 12 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 12 0 23 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _