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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PGK2 All Species: 16.36
Human Site: S186 Identified Species: 25.71
UniProt: P07205 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P07205 NP_620061.2 417 44796 S186 V N L P H K A S G F L M K K E
Chimpanzee Pan troglodytes XP_518531 417 44783 S186 V H L P H K A S G F L M K K E
Rhesus Macaque Macaca mulatta XP_001105356 417 44861 S186 V N L P H K A S G F L M K K E
Dog Lupus familis XP_532167 417 44727 S186 V N L P Q K A S G F L M K K E
Cat Felis silvestris
Mouse Mus musculus P09411 417 44532 G186 V N L P Q K A G G F L M K K E
Rat Rattus norvegicus P16617 417 44520 G186 V N L P Q K A G G F L M K K E
Wallaby Macropus eugenll P29408 417 44960 C186 V N L P Q K A C G F L M K K E
Platypus Ornith. anatinus XP_001507304 570 61329 A339 V N L P Q K A A G F L M K K E
Chicken Gallus gallus P51903 417 44698 A186 V H L P Q K A A G F L M K K E
Frog Xenopus laevis NP_001086928 417 44564 A186 V K L P Q R A A G F L M K K E
Zebra Danio Brachydanio rerio NP_998552 417 44672 A186 V N L P Q K A A G F L M K K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q01604 415 43843 A184 D G F E Q R A A G L L L N K E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P91427 417 44094 S185 V E H S Q R A S G F L L K N E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P00560 416 44720 A184 F D L P Q R A A G F L L E K E
Red Bread Mold Neurospora crassa P38667 418 45038 A186 I D L P V K A A G F L M K K E
Conservation
Percent
Protein Identity: 100 99.5 97.8 90.1 N.A. 85.6 86 82.9 58.5 82.4 79.6 81 N.A. 67.8 N.A. 69 N.A.
Protein Similarity: 100 100 98.3 94.9 N.A. 94 94.4 91.8 68 93 91.1 89.2 N.A. 82.7 N.A. 81.7 N.A.
P-Site Identity: 100 93.3 100 93.3 N.A. 86.6 86.6 86.6 86.6 80 73.3 86.6 N.A. 33.3 N.A. 53.3 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 86.6 86.6 93.3 93.3 86.6 93.3 N.A. 53.3 N.A. 66.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 62.5 65.5
Protein Similarity: N.A. N.A. N.A. N.A. 75.7 77.9
P-Site Identity: N.A. N.A. N.A. N.A. 53.3 73.3
P-Site Similarity: N.A. N.A. N.A. N.A. 86.6 93.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 100 47 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 7 14 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 7 0 7 0 0 0 0 0 0 0 0 7 0 100 % E
% Phe: 7 0 7 0 0 0 0 0 0 94 0 0 0 0 0 % F
% Gly: 0 7 0 0 0 0 0 14 100 0 0 0 0 0 0 % G
% His: 0 14 7 0 20 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 7 0 0 0 74 0 0 0 0 0 0 87 94 0 % K
% Leu: 0 0 87 0 0 0 0 0 0 7 100 20 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 80 0 0 0 % M
% Asn: 0 54 0 0 0 0 0 0 0 0 0 0 7 7 0 % N
% Pro: 0 0 0 87 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 74 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 27 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 7 0 0 0 34 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 80 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _