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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEXA
All Species:
31.82
Human Site:
T231
Identified Species:
58.33
UniProt:
P06865
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06865
NP_000511.2
529
60689
T231
K
G
S
Y
N
P
V
T
H
I
Y
T
A
Q
D
Chimpanzee
Pan troglodytes
XP_001175122
529
60636
T231
K
G
S
Y
N
P
V
T
H
I
Y
T
A
Q
D
Rhesus Macaque
Macaca mulatta
XP_001092589
529
60742
T231
K
G
S
Y
N
P
V
T
H
I
Y
T
A
Q
D
Dog
Lupus familis
XP_544758
529
60532
T231
K
G
S
Y
N
P
A
T
H
I
Y
T
A
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
P29416
528
60581
T231
K
G
S
F
N
P
V
T
H
I
Y
T
A
Q
D
Rat
Rattus norvegicus
Q641X3
528
60520
T231
K
G
S
F
N
P
V
T
H
I
Y
T
A
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513475
574
64498
S279
N
Q
G
S
Y
S
H
S
H
V
Y
T
P
T
D
Chicken
Gallus gallus
NP_001025561
526
58930
T230
Q
G
A
F
N
A
M
T
H
V
Y
T
A
S
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001017763
532
60708
T236
K
G
A
F
H
P
F
T
H
I
Y
T
Q
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8WSF3
660
75468
E340
H
G
A
Y
S
E
S
E
T
Y
S
E
Q
D
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22492
555
64361
R233
G
V
G
A
Y
S
P
R
H
V
Y
S
R
E
D
Sea Urchin
Strong. purpuratus
XP_799340
543
61806
Q249
S
R
M
N
A
Y
D
Q
N
H
V
Y
T
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001142218
433
49746
P165
V
L
A
E
F
D
T
P
G
H
T
L
S
W
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.7
81.8
N.A.
84.1
82.8
N.A.
54.5
66.1
N.A.
55.2
N.A.
27.7
N.A.
38.3
49.3
Protein Similarity:
100
99.8
99.2
90.7
N.A.
91.1
90.3
N.A.
66.7
78
N.A.
69.9
N.A.
41.6
N.A.
54.2
64.4
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
26.6
53.3
N.A.
60
N.A.
13.3
N.A.
20
0
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
40
86.6
N.A.
80
N.A.
26.6
N.A.
40
20
Percent
Protein Identity:
N.A.
70.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
77.3
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
31
8
8
8
8
0
0
0
0
0
54
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
8
0
0
0
0
0
0
8
77
% D
% Glu:
0
0
0
8
0
8
0
8
0
0
0
8
0
8
8
% E
% Phe:
0
0
0
31
8
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
70
16
0
0
0
0
0
8
0
0
0
0
0
8
% G
% His:
8
0
0
0
8
0
8
0
77
16
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
54
0
0
0
0
0
% I
% Lys:
54
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% L
% Met:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
54
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
54
8
8
0
0
0
0
8
0
0
% P
% Gln:
8
8
0
0
0
0
0
8
0
0
0
0
16
47
0
% Q
% Arg:
0
8
0
0
0
0
0
8
0
0
0
0
8
8
0
% R
% Ser:
8
0
47
8
8
16
8
8
0
0
8
8
8
16
0
% S
% Thr:
0
0
0
0
0
0
8
62
8
0
8
70
8
8
0
% T
% Val:
8
8
0
0
0
0
39
0
0
24
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
39
16
8
0
0
0
8
77
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _