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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEXA
All Species:
19.09
Human Site:
S51
Identified Species:
35
UniProt:
P06865
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06865
NP_000511.2
529
60689
S51
F
Q
F
Q
Y
D
V
S
S
A
A
Q
P
G
C
Chimpanzee
Pan troglodytes
XP_001175122
529
60636
S51
F
Q
F
Q
Y
D
V
S
S
A
A
Q
P
G
C
Rhesus Macaque
Macaca mulatta
XP_001092589
529
60742
S51
F
Q
F
Q
Y
D
I
S
S
A
A
Q
P
G
C
Dog
Lupus familis
XP_544758
529
60532
S51
F
Q
F
R
Y
H
S
S
S
A
A
Q
P
G
C
Cat
Felis silvestris
Mouse
Mus musculus
P29416
528
60581
S51
F
Q
F
R
Y
H
V
S
S
A
A
Q
G
G
C
Rat
Rattus norvegicus
Q641X3
528
60520
G51
F
Q
F
R
Y
H
A
G
S
A
A
Q
A
G
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513475
574
64498
S100
D
I
S
H
G
P
G
S
S
A
G
P
A
C
S
Chicken
Gallus gallus
NP_001025561
526
58930
A51
A
R
F
H
F
A
H
A
A
G
S
A
V
G
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001017763
532
60708
S56
Q
L
F
T
F
T
Y
S
Q
D
S
A
A
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8WSF3
660
75468
G155
I
Q
R
L
D
Y
V
G
S
S
S
E
P
T
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22492
555
64361
D53
K
N
R
T
I
T
Y
D
K
I
G
I
D
L
G
Sea Urchin
Strong. purpuratus
XP_799340
543
61806
A71
E
S
Q
F
M
F
T
A
N
K
V
Q
C
D
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001142218
433
49746
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.7
81.8
N.A.
84.1
82.8
N.A.
54.5
66.1
N.A.
55.2
N.A.
27.7
N.A.
38.3
49.3
Protein Similarity:
100
99.8
99.2
90.7
N.A.
91.1
90.3
N.A.
66.7
78
N.A.
69.9
N.A.
41.6
N.A.
54.2
64.4
P-Site Identity:
100
100
93.3
80
N.A.
80
66.6
N.A.
20
13.3
N.A.
13.3
N.A.
26.6
N.A.
0
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
73.3
N.A.
20
46.6
N.A.
26.6
N.A.
46.6
N.A.
0
20
Percent
Protein Identity:
N.A.
70.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
77.3
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
8
16
8
54
47
16
24
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
47
% C
% Asp:
8
0
0
0
8
24
0
8
0
8
0
0
8
8
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
47
0
62
8
16
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
8
16
0
8
16
0
8
54
8
% G
% His:
0
0
0
16
0
24
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
8
0
8
0
0
8
0
8
0
0
8
% I
% Lys:
8
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% K
% Leu:
0
8
0
8
0
0
0
0
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
8
39
0
8
% P
% Gln:
8
54
8
24
0
0
0
0
8
0
0
54
0
8
0
% Q
% Arg:
0
8
16
24
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
8
0
0
0
8
54
62
8
24
0
0
0
8
% S
% Thr:
0
0
0
16
0
16
8
0
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
31
0
0
0
8
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
47
8
16
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _