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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BCHE
All Species:
24.85
Human Site:
Y505
Identified Species:
42.05
UniProt:
P06276
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06276
NP_000046.1
602
68418
Y505
R
W
A
N
F
A
K
Y
G
N
P
N
E
T
Q
Chimpanzee
Pan troglodytes
XP_516857
643
72946
Y546
R
W
A
N
F
A
K
Y
G
N
P
N
E
T
Q
Rhesus Macaque
Macaca mulatta
P32751
141
15206
G50
L
I
W
I
Y
G
G
G
F
Q
T
G
T
S
S
Dog
Lupus familis
XP_545267
602
68500
Y505
Y
W
A
T
F
A
K
Y
G
H
P
D
G
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q03311
603
68503
Y506
T
W
A
N
F
A
K
Y
G
H
P
N
G
T
Q
Rat
Rattus norvegicus
P37136
614
68178
T517
Y
W
T
N
F
A
R
T
G
D
P
N
D
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505841
602
68511
T505
Y
W
A
S
F
A
K
T
G
N
P
N
G
T
Q
Chicken
Gallus gallus
P36196
767
83002
R671
R
Y
W
G
N
F
A
R
T
G
D
P
N
G
G
Frog
Xenopus laevis
NP_001121332
600
68177
G504
W
A
N
F
A
R
T
G
D
P
N
E
G
N
D
Zebra Danio
Brachydanio rerio
Q9DDE3
634
71980
N538
F
A
R
T
G
N
P
N
V
N
T
D
G
T
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07140
649
71767
T557
A
V
I
E
F
A
K
T
G
N
P
A
Q
D
G
Honey Bee
Apis mellifera
XP_393751
657
73886
P546
N
F
A
K
T
G
D
P
N
V
G
D
V
D
V
Nematode Worm
Caenorhab. elegans
P38433
620
71415
T508
Y
W
A
N
F
A
K
T
G
D
P
N
K
N
E
Sea Urchin
Strong. purpuratus
XP_782113
508
56946
D417
H
D
P
V
K
L
R
D
G
V
D
F
A
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
22.7
86.7
N.A.
79.2
51.6
N.A.
77.7
38.7
51.1
52
N.A.
35.7
40.4
40.8
38.7
Protein Similarity:
100
92.8
23.4
91.1
N.A.
87.5
68.2
N.A.
87.3
51.6
69.5
69.4
N.A.
52.2
57.3
57.7
52.1
P-Site Identity:
100
100
0
66.6
N.A.
80
46.6
N.A.
73.3
6.6
0
13.3
N.A.
40
6.6
60
6.6
P-Site Similarity:
100
100
13.3
80
N.A.
86.6
73.3
N.A.
80
13.3
0
20
N.A.
46.6
20
80
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
50
0
8
58
8
0
0
0
0
8
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
8
8
8
15
15
22
8
15
8
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
8
15
0
8
% E
% Phe:
8
8
0
8
58
8
0
0
8
0
0
8
0
0
0
% F
% Gly:
0
0
0
8
8
15
8
15
65
8
8
8
36
8
22
% G
% His:
8
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% H
% Ile:
0
8
8
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
8
0
50
0
0
0
0
0
8
0
0
% K
% Leu:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
8
36
8
8
0
8
8
36
8
43
8
15
0
% N
% Pro:
0
0
8
0
0
0
8
8
0
8
58
8
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
36
% Q
% Arg:
22
0
8
0
0
8
15
8
0
0
0
0
0
0
8
% R
% Ser:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
8
% S
% Thr:
8
0
8
15
8
0
8
29
8
0
15
0
8
43
0
% T
% Val:
0
8
0
8
0
0
0
0
8
15
0
0
8
0
8
% V
% Trp:
8
50
15
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
29
8
0
0
8
0
0
29
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _