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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALPL
All Species:
22.73
Human Site:
T405
Identified Species:
41.67
UniProt:
P05186
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05186
NP_000469.3
524
57305
T405
L
A
P
M
L
S
D
T
D
K
K
P
F
T
A
Chimpanzee
Pan troglodytes
XP_001142681
961
103936
Q835
G
L
A
P
S
K
A
Q
D
S
K
A
Y
T
S
Rhesus Macaque
Macaca mulatta
XP_001109717
652
71041
T533
L
A
P
M
L
S
D
T
D
K
K
P
F
T
A
Dog
Lupus familis
XP_535374
522
57256
T402
L
A
P
M
V
S
D
T
D
K
K
P
F
T
A
Cat
Felis silvestris
Mouse
Mus musculus
P09242
524
57437
T405
L
A
P
M
V
S
D
T
D
K
K
P
F
T
A
Rat
Rattus norvegicus
P08289
524
57641
T405
L
A
P
M
V
S
D
T
D
K
K
P
F
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92058
519
56742
I394
Y
T
P
R
G
N
P
I
F
G
L
A
P
M
Q
Frog
Xenopus laevis
NP_001080895
526
57659
V405
L
A
P
V
P
S
D
V
D
Q
K
P
F
T
S
Zebra Danio
Brachydanio rerio
NP_001014375
532
58340
E411
G
L
A
P
K
Q
A
E
D
D
L
P
Y
T
S
Tiger Blowfish
Takifugu rubipres
NP_001027823
527
57490
V408
L
A
P
A
V
S
D
V
D
Q
K
P
F
T
A
Fruit Fly
Dros. melanogaster
Q24238
596
65244
G455
E
T
I
S
Y
A
N
G
P
G
Y
W
D
H
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130844
524
57641
T405
L
A
P
M
V
S
D
T
D
K
K
P
F
T
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11491
566
62986
I435
E
N
F
I
K
H
E
I
L
E
K
D
L
G
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.6
78.2
87.9
N.A.
89.8
90.8
N.A.
N.A.
74.8
72
57.8
71.9
38.5
N.A.
N.A.
N.A.
Protein Similarity:
100
41.9
79.4
93.6
N.A.
94.4
95
N.A.
N.A.
83.7
84
69.9
81.4
53
N.A.
N.A.
N.A.
P-Site Identity:
100
20
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
6.6
66.6
20
73.3
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
N.A.
13.3
86.6
33.3
86.6
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
90.8
N.A.
N.A.
26.3
N.A.
Protein Similarity:
N.A.
95
N.A.
N.A.
43.6
N.A.
P-Site Identity:
N.A.
93.3
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
100
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
62
16
8
0
8
16
0
0
0
0
16
0
0
54
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
62
0
77
8
0
8
8
0
0
% D
% Glu:
16
0
0
0
0
0
8
8
0
8
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
8
0
0
0
62
0
0
% F
% Gly:
16
0
0
0
8
0
0
8
0
16
0
0
0
8
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
8
8
0
0
0
16
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
16
8
0
0
0
47
77
0
0
0
0
% K
% Leu:
62
16
0
0
16
0
0
0
8
0
16
0
8
0
8
% L
% Met:
0
0
0
47
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
8
0
0
0
8
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
70
16
8
0
8
0
8
0
0
70
8
0
0
% P
% Gln:
0
0
0
0
0
8
0
8
0
16
0
0
0
0
8
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
8
8
62
0
0
0
8
0
0
0
0
24
% S
% Thr:
0
16
0
0
0
0
0
47
0
0
0
0
0
77
0
% T
% Val:
0
0
0
8
39
0
0
16
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
8
0
0
0
8
0
0
0
0
0
8
0
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _