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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALPL
All Species:
0
Human Site:
T255
Identified Species:
0
UniProt:
P05186
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05186
NP_000469.3
524
57305
T255
D
G
L
D
L
V
D
T
W
K
S
F
K
P
R
Chimpanzee
Pan troglodytes
XP_001142681
961
103936
V253
R
L
D
G
K
N
L
V
Q
E
W
L
A
K
H
Rhesus Macaque
Macaca mulatta
XP_001109717
652
71041
I383
D
G
L
D
L
V
N
I
W
K
S
F
K
P
R
Dog
Lupus familis
XP_535374
522
57256
I252
D
G
L
N
L
I
D
I
W
K
N
F
K
P
R
Cat
Felis silvestris
Mouse
Mus musculus
P09242
524
57437
I255
D
G
L
D
L
I
S
I
W
K
S
F
K
P
R
Rat
Rattus norvegicus
P08289
524
57641
I255
D
G
L
D
L
I
S
I
W
K
S
F
K
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92058
519
56742
A254
D
G
K
D
L
V
Q
A
W
H
D
T
K
P
A
Frog
Xenopus laevis
NP_001080895
526
57659
I255
D
G
L
N
L
T
Q
I
W
L
D
Q
K
P
N
Zebra Danio
Brachydanio rerio
NP_001014375
532
58340
N262
K
D
K
K
N
L
I
N
V
W
L
N
A
R
K
Tiger Blowfish
Takifugu rubipres
NP_001027823
527
57490
G258
K
D
G
R
N
L
V
G
E
W
I
E
K
M
E
Fruit Fly
Dros. melanogaster
Q24238
596
65244
W291
N
R
N
L
P
A
E
W
L
A
H
H
A
N
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130844
524
57641
I255
D
G
L
D
L
I
S
I
W
K
S
F
K
P
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11491
566
62986
V269
L
K
S
H
G
E
N
V
T
L
P
F
L
G
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.6
78.2
87.9
N.A.
89.8
90.8
N.A.
N.A.
74.8
72
57.8
71.9
38.5
N.A.
N.A.
N.A.
Protein Similarity:
100
41.9
79.4
93.6
N.A.
94.4
95
N.A.
N.A.
83.7
84
69.9
81.4
53
N.A.
N.A.
N.A.
P-Site Identity:
100
0
86.6
73.3
N.A.
80
80
N.A.
N.A.
53.3
46.6
0
6.6
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
93.3
93.3
N.A.
86.6
86.6
N.A.
N.A.
53.3
53.3
13.3
13.3
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
90.8
N.A.
N.A.
26.3
N.A.
Protein Similarity:
N.A.
95
N.A.
N.A.
43.6
N.A.
P-Site Identity:
N.A.
80
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
86.6
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
8
0
8
0
0
24
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
62
16
8
47
0
0
16
0
0
0
16
0
0
0
8
% D
% Glu:
0
0
0
0
0
8
8
0
8
8
0
8
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
54
0
0
0
% F
% Gly:
0
62
8
8
8
0
0
8
0
0
0
0
0
8
0
% G
% His:
0
0
0
8
0
0
0
0
0
8
8
8
0
0
8
% H
% Ile:
0
0
0
0
0
31
8
47
0
0
8
0
0
0
0
% I
% Lys:
16
8
16
8
8
0
0
0
0
47
0
0
70
8
8
% K
% Leu:
8
8
54
8
62
16
8
0
8
16
8
8
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
0
8
16
16
8
16
8
0
0
8
8
0
8
8
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
8
0
0
62
0
% P
% Gln:
0
0
0
0
0
0
16
0
8
0
0
8
0
0
0
% Q
% Arg:
8
8
0
8
0
0
0
0
0
0
0
0
0
8
47
% R
% Ser:
0
0
8
0
0
0
24
0
0
0
39
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
8
8
0
0
8
0
0
0
% T
% Val:
0
0
0
0
0
24
8
16
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
62
16
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _