KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALPL
All Species:
39.39
Human Site:
T141
Identified Species:
72.22
UniProt:
P05186
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05186
NP_000469.3
524
57305
T141
T
E
R
S
R
C
N
T
T
Q
G
N
E
V
T
Chimpanzee
Pan troglodytes
XP_001142681
961
103936
T142
A
R
F
N
Q
C
N
T
T
R
G
N
E
V
I
Rhesus Macaque
Macaca mulatta
XP_001109717
652
71041
T269
T
E
R
S
R
C
N
T
T
Q
G
N
E
V
T
Dog
Lupus familis
XP_535374
522
57256
T138
T
Q
R
T
Q
C
N
T
T
Q
G
N
E
V
T
Cat
Felis silvestris
Mouse
Mus musculus
P09242
524
57437
T141
T
E
R
T
R
C
N
T
T
Q
G
N
E
V
T
Rat
Rattus norvegicus
P08289
524
57641
T141
T
E
R
T
R
C
N
T
T
Q
G
N
E
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92058
519
56742
T140
V
T
R
D
R
C
N
T
T
K
G
Q
E
V
T
Frog
Xenopus laevis
NP_001080895
526
57659
T141
A
V
R
N
Q
C
N
T
S
K
G
N
E
V
D
Zebra Danio
Brachydanio rerio
NP_001014375
532
58340
T151
A
V
A
Y
E
C
N
T
T
F
G
N
E
V
F
Tiger Blowfish
Takifugu rubipres
NP_001027823
527
57490
T145
A
V
R
S
Q
C
N
T
T
K
G
N
E
V
T
Fruit Fly
Dros. melanogaster
Q24238
596
65244
N172
D
A
T
R
S
K
K
N
G
Q
Q
G
R
V
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130844
524
57641
T141
T
E
R
T
R
C
N
T
T
Q
G
N
E
V
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11491
566
62986
L154
H
R
P
C
G
T
V
L
E
A
A
K
L
A
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.6
78.2
87.9
N.A.
89.8
90.8
N.A.
N.A.
74.8
72
57.8
71.9
38.5
N.A.
N.A.
N.A.
Protein Similarity:
100
41.9
79.4
93.6
N.A.
94.4
95
N.A.
N.A.
83.7
84
69.9
81.4
53
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
100
80
N.A.
93.3
93.3
N.A.
N.A.
66.6
53.3
53.3
73.3
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
73.3
100
100
N.A.
100
100
N.A.
N.A.
73.3
80
53.3
86.6
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
90.8
N.A.
N.A.
26.3
N.A.
Protein Similarity:
N.A.
95
N.A.
N.A.
43.6
N.A.
P-Site Identity:
N.A.
93.3
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
100
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
8
8
0
0
0
0
0
0
8
8
0
0
8
0
% A
% Cys:
0
0
0
8
0
85
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
39
0
0
8
0
0
0
8
0
0
0
85
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
8
% F
% Gly:
0
0
0
0
8
0
0
0
8
0
85
8
0
0
8
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
8
8
0
0
24
0
8
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
16
0
0
85
8
0
0
0
77
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
31
0
0
0
0
54
8
8
0
0
8
% Q
% Arg:
0
16
70
8
47
0
0
0
0
8
0
0
8
0
0
% R
% Ser:
0
0
0
24
8
0
0
0
8
0
0
0
0
0
0
% S
% Thr:
47
8
8
31
0
8
0
85
77
0
0
0
0
0
62
% T
% Val:
8
24
0
0
0
0
8
0
0
0
0
0
0
93
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _