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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALPL
All Species:
22.73
Human Site:
S198
Identified Species:
41.67
UniProt:
P05186
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05186
NP_000469.3
524
57305
S198
E
M
P
P
E
A
L
S
Q
G
C
K
D
I
A
Chimpanzee
Pan troglodytes
XP_001142681
961
103936
Q632
D
M
P
A
S
A
R
Q
D
G
C
Q
D
I
A
Rhesus Macaque
Macaca mulatta
XP_001109717
652
71041
S326
E
M
P
P
E
A
L
S
Q
G
C
K
D
I
A
Dog
Lupus familis
XP_535374
522
57256
S195
E
M
P
P
E
A
L
S
Q
G
C
K
D
I
A
Cat
Felis silvestris
Mouse
Mus musculus
P09242
524
57437
S198
E
M
P
P
E
A
L
S
Q
G
C
K
D
I
A
Rat
Rattus norvegicus
P08289
524
57641
S198
E
M
P
P
E
A
L
S
Q
G
C
K
D
I
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92058
519
56742
E197
E
M
P
L
D
A
L
E
G
G
C
K
D
I
A
Frog
Xenopus laevis
NP_001080895
526
57659
E198
E
M
P
K
E
A
V
E
Q
G
C
K
D
I
A
Zebra Danio
Brachydanio rerio
NP_001014375
532
58340
R208
D
V
P
S
E
A
R
R
Q
G
C
K
D
I
A
Tiger Blowfish
Takifugu rubipres
NP_001027823
527
57490
Q202
V
M
P
A
E
A
V
Q
D
G
C
K
D
I
A
Fruit Fly
Dros. melanogaster
Q24238
596
65244
G229
E
V
P
A
E
S
V
G
F
H
V
D
I
A
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130844
524
57641
S198
E
M
P
P
E
A
L
S
Q
G
C
K
D
I
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11491
566
62986
M211
G
R
V
V
D
L
L
M
G
G
G
R
S
H
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.6
78.2
87.9
N.A.
89.8
90.8
N.A.
N.A.
74.8
72
57.8
71.9
38.5
N.A.
N.A.
N.A.
Protein Similarity:
100
41.9
79.4
93.6
N.A.
94.4
95
N.A.
N.A.
83.7
84
69.9
81.4
53
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
100
100
N.A.
100
100
N.A.
N.A.
73.3
80
66.6
66.6
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
66.6
100
100
N.A.
100
100
N.A.
N.A.
80
86.6
80
73.3
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
90.8
N.A.
N.A.
26.3
N.A.
Protein Similarity:
N.A.
95
N.A.
N.A.
43.6
N.A.
P-Site Identity:
N.A.
100
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
100
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
24
0
85
0
0
0
0
0
0
0
8
85
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
85
0
0
0
0
% C
% Asp:
16
0
0
0
16
0
0
0
16
0
0
8
85
0
0
% D
% Glu:
70
0
0
0
77
0
0
16
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% F
% Gly:
8
0
0
0
0
0
0
8
16
93
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
8
85
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
77
0
0
0
% K
% Leu:
0
0
0
8
0
8
62
0
0
0
0
0
0
0
0
% L
% Met:
0
77
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
93
47
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
16
62
0
0
8
0
0
0
% Q
% Arg:
0
8
0
0
0
0
16
8
0
0
0
8
0
0
8
% R
% Ser:
0
0
0
8
8
8
0
47
0
0
0
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
16
8
8
0
0
24
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _