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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP1A2
All Species:
30.61
Human Site:
T390
Identified Species:
84.17
UniProt:
P05177
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05177
NP_000752.2
515
58294
T390
P
F
T
I
P
H
S
T
T
R
D
T
T
L
N
Chimpanzee
Pan troglodytes
XP_001135509
501
55792
Y385
D
T
T
L
N
G
F
Y
I
P
K
K
C
C
V
Rhesus Macaque
Macaca mulatta
Q6GUR1
512
58111
T390
P
F
T
I
P
H
S
T
T
R
D
T
S
L
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P00186
513
58165
T388
P
F
T
I
P
H
S
T
T
R
D
T
S
L
N
Rat
Rattus norvegicus
P04799
513
58241
T388
P
F
T
I
P
H
S
T
T
R
D
T
S
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511800
519
59024
T396
P
F
T
I
P
H
S
T
T
R
A
T
T
L
N
Chicken
Gallus gallus
P79761
528
60053
T399
P
F
T
I
P
H
S
T
T
R
D
T
V
L
N
Frog
Xenopus laevis
NP_001090541
526
59855
T398
P
F
T
I
P
H
C
T
T
K
D
T
V
L
N
Zebra Danio
Brachydanio rerio
NP_571954
519
58541
T395
P
F
T
I
P
H
C
T
S
K
D
T
S
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.5
72.2
N.A.
N.A.
72.6
74.9
N.A.
64.7
61.7
56.6
53.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
90.2
84.6
N.A.
N.A.
87.5
88.5
N.A.
79
75.9
74.9
71
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
86.6
N.A.
N.A.
93.3
93.3
N.A.
93.3
93.3
80
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
93.3
N.A.
N.A.
100
100
N.A.
93.3
93.3
86.6
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
23
0
0
0
0
0
12
12
0
% C
% Asp:
12
0
0
0
0
0
0
0
0
0
78
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
89
0
0
0
0
12
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
89
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
89
0
0
0
0
12
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
23
12
12
0
0
12
% K
% Leu:
0
0
0
12
0
0
0
0
0
0
0
0
0
89
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
78
% N
% Pro:
89
0
0
0
89
0
0
0
0
12
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
67
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
67
0
12
0
0
0
45
0
0
% S
% Thr:
0
12
100
0
0
0
0
89
78
0
0
89
23
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
23
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _