Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCCB All Species: 33.03
Human Site: S524 Identified Species: 60.56
UniProt: P05166 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P05166 NP_000523.2 539 58216 S524 C D L D V L A S K K V Q R P W
Chimpanzee Pan troglodytes XP_001150022 595 64057 S580 C D L D V L A S K K V Q R P W
Rhesus Macaque Macaca mulatta XP_001114982 539 58170 S524 C D L D V L A S K K V Q R P W
Dog Lupus familis XP_534271 554 59958 S539 R D L D V L A S K K V Q R P W
Cat Felis silvestris
Mouse Mus musculus Q99MN9 541 58375 S526 C D L E V L A S K K V H R P W
Rat Rattus norvegicus P07633 541 58608 S526 C D L E V L A S K K V H R P W
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001231794 713 76377 S698 H D L D V L A S K T Q S N P W
Frog Xenopus laevis NP_001083656 541 59015 S526 R D L E V L A S K Q Q V N P W
Zebra Danio Brachydanio rerio NP_998090 557 60772 S540 R D L E V L A S K K Q T N P C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V9A7 578 62630 N565 L S L K A A L N N A G Q E T K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34385 608 66505 T582 G V I D P K D T R K V L G L A
Sea Urchin Strong. purpuratus XP_796906 543 59143 G528 R D L D L L A G K Q Q S N P P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LDD8 587 63994 N574 L C L S A A L N R P L E D T R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90 99 92.4 N.A. 92.2 91.3 N.A. N.A. 65.3 83.5 80.6 N.A. 34 N.A. 26.9 75.8
Protein Similarity: 100 90.4 99.4 94.7 N.A. 96.4 96.1 N.A. N.A. 71.2 91.3 87.6 N.A. 49.1 N.A. 43.4 84.9
P-Site Identity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. N.A. 66.6 60 60 N.A. 13.3 N.A. 20 46.6
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 66.6 73.3 66.6 N.A. 20 N.A. 40 60
Percent
Protein Identity: N.A. N.A. N.A. 28.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 16 16 77 0 0 8 0 0 0 0 8 % A
% Cys: 39 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 77 0 54 0 0 8 0 0 0 0 0 8 0 0 % D
% Glu: 0 0 0 31 0 0 0 0 0 0 0 8 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 0 0 0 8 0 0 8 0 8 0 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 16 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 8 0 8 0 0 77 62 0 0 0 0 8 % K
% Leu: 16 0 93 0 8 77 16 0 0 0 8 8 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 16 8 0 0 0 31 0 0 % N
% Pro: 0 0 0 0 8 0 0 0 0 8 0 0 0 77 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 16 31 39 0 0 0 % Q
% Arg: 31 0 0 0 0 0 0 0 16 0 0 0 47 0 8 % R
% Ser: 0 8 0 8 0 0 0 70 0 0 0 16 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 8 0 8 0 8 0 16 0 % T
% Val: 0 8 0 0 70 0 0 0 0 0 54 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 62 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _