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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPINB2
All Species:
22.12
Human Site:
Y121
Identified Species:
54.07
UniProt:
P05120
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05120
NP_001137290.1
415
46596
Y121
I
N
A
S
T
G
N
Y
L
L
E
S
V
N
K
Chimpanzee
Pan troglodytes
XP_001148522
415
46641
Y121
I
N
A
S
T
G
D
Y
L
L
E
S
V
N
K
Rhesus Macaque
Macaca mulatta
XP_001092329
415
46507
Y121
I
N
A
S
T
G
D
Y
L
L
E
S
V
N
K
Dog
Lupus familis
XP_851985
537
59430
Y241
V
S
A
A
S
G
E
Y
L
L
E
S
V
N
Q
Cat
Felis silvestris
Mouse
Mus musculus
P12388
415
46273
Y121
I
N
T
P
Q
G
D
Y
L
L
E
S
A
N
K
Rat
Rattus norvegicus
P29524
416
47229
D121
I
N
T
P
R
L
G
D
Y
L
L
E
S
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514003
515
59038
Y221
V
N
K
S
S
E
V
Y
V
L
E
S
A
N
K
Chicken
Gallus gallus
O73790
410
47365
A117
N
N
Y
S
L
R
S
A
N
R
I
Y
V
E
K
Frog
Xenopus laevis
Q52L45
377
42679
E96
L
A
N
R
L
F
G
E
K
T
F
N
F
L
P
Zebra Danio
Brachydanio rerio
NP_001103200
439
48627
Y142
L
N
K
P
G
A
P
Y
V
L
S
L
A
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
94.6
60.1
N.A.
75.9
72.5
N.A.
48.7
40.7
44
44.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
97.5
67.4
N.A.
86.2
85.5
N.A.
62.7
62.8
63.6
63.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
60
N.A.
66.6
20
N.A.
53.3
26.6
0
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
73.3
20
N.A.
73.3
33.3
13.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
40
10
0
10
0
10
0
0
0
0
30
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
30
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
10
10
0
0
60
10
0
10
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
10
0
10
0
0
% F
% Gly:
0
0
0
0
10
50
20
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
50
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
20
0
0
0
0
0
10
0
0
0
0
0
60
% K
% Leu:
20
0
0
0
20
10
0
0
50
80
10
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
80
10
0
0
0
10
0
10
0
0
10
0
70
10
% N
% Pro:
0
0
0
30
0
0
10
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
10
10
10
0
0
0
10
0
0
0
0
10
% R
% Ser:
0
10
0
50
20
0
10
0
0
0
10
60
10
0
0
% S
% Thr:
0
0
20
0
30
0
0
0
0
10
0
0
0
0
0
% T
% Val:
20
0
0
0
0
0
10
0
20
0
0
0
50
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
70
10
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _